KLHDC7B-DT aggravates pancreatic ductal adenocarcinoma development via inducing the crosstalk between cancer cells and macrophages.
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Summary
The crosstalk between PDAC cells and macrophages induced by KLHDC7B-DT represents potential therapeutic target for PDAC.
- Type
- article
- Published
- 2021-02-01
- Cited by
- 19
- References
- 66
- Access
- Open access
- OpenAlex
- https://openalex.org/W3128148170
- Semantic Scholar
- https://api.semanticscholar.org/CorpusID:231806177
Keywords
Autocrine signalling, Paracrine signalling, STAT3, Cancer research, Pancreatic cancer
References
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- Evolution and functions of long noncoding RNAs.
- Interleukin-6 signaling promotes alternative macrophage activation to limit obesity-associated insulin resistance and endotoxemia
- Macrophage polarization in pancreatic carcinoma: role of heparanase enzyme.
- Long non-coding RNA DILC regulates liver cancer stem cells via IL-6/STAT3 axis.
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- Long noncoding RNA glypican 3 (GPC3) antisense transcript 1 promotes hepatocellular carcinoma progression via epigenetically activating GPC3
- IL-6 promotes M2 macrophage polarization by modulating purinergic signaling and regulates the lethal release of nitric oxide during Trypanosoma cruzi infection.
- An alternative POLDIP3 transcript promotes hepatocellular carcinoma progression.
- The MBNL3 splicing factor promotes hepatocellular carcinoma by increasing PXN expression through the alternative splicing of lncRNA-PXN-AS1
- IL-6 Regulates M2 Polarization and Local Proliferation of Adipose Tissue Macrophages in Obesity
- Long noncoding RNA MRCCAT1 promotes metastasis of clear cell renal cell carcinoma via inhibiting NPR3 and activating p38-MAPK signaling
- FEZF1-AS1/miR-107/ZNF312B axis facilitates progression and Warburg effect in pancreatic ductal adenocarcinoma
Cited by
- Missing links - epigenetic regulators of the pancreatic cancer-associated inflammation.
- Chromatin accessibility and transcriptome integrative analysis revealed AP-1-mediated genes potentially modulate histopathology features in psoriasis
- Long non-coding RNAs and cancer mechanisms: Immune cells and inflammatory cytokines in the tumor microenvironment
- Exosome-derived FGD5-AS1 promotes tumor-associated macrophage M2 polarization-mediated pancreatic cancer cell proliferation and metastasis.
- Depletion of BATF in CAR-T cells enhances antitumor activity by inducing resistance against exhaustion and formation of central memory cells.
- Construction and validation of a macrophage polarization-related prognostic index to predict the overall survival in patients with early-stage triple-negative breast cancer
- Noncoding RNAs as regulators of STAT3 pathway in gastrointestinal cancers: Roles in cancer progression and therapeutic response
- T2DB: A Web Database for Long Non-Coding RNA Genes in Type II Diabetes
- A network-based approach reveals long non-coding RNAs associated with disease activity in lupus nephritis: key pathways for flare and potential biomarkers to be used as liquid biopsies
- Long non-coding RNAs and pancreatic cancer: A multifaceted view.
- The regulatory relationship between transcription factor STAT3 and noncoding RNA
- LncRNAs exhibit subtype-specific expression, survival associations, and cancer-promoting effects in breast cancer.
- Interplay between JAK/STAT pathway and non-coding RNAs in different cancers
- Long non-coding RNAs: Emerging regulators of invasion and metastasis in pancreatic cancer
- The Role of PANoptosis-Related Genes in Predicting Breast Cancer Survival and Immune Prospect
- Mechanisms of Macrophage Polarization Regulated by Oridonin: A Review
- Construction and validation of a prognostic risk model for cuproptosis-related lncrna in breast cancer
- Additional file 4 of MNMST: topology of cell networks leverages identification of spatial domains from spatial transcriptomics data
- Additional file 4 of MNMST: topology of cell networks leverages identification of spatial domains from spatial transcriptomics data
- Additional file 1 of MNMST: topology of cell networks leverages identification of spatial domains from spatial transcriptomics data
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