Glomerular Endothelial Cells as Instigators of Glomerular Sclerotic Diseases
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Summary
This review summarizes literature that uncovers the importance of cross-talk between GEnC and podocytes, and GEnCs and mesangial cells in the context of the development of FSGS and DN, and the potential use of G EnCs as efficacious cellular target to pharmacologically halt development and progression of DN and FSGS.
- Type
- review
- Published
- 2020-10-06
- Cited by
- 73
- References
- 146
- Access
- Open access
- OpenAlex
- https://openalex.org/W3091904231
- Semantic Scholar
- https://api.semanticscholar.org/CorpusID:222135636
Keywords
Podocyte, Focal segmental glomerulosclerosis, Glomerulosclerosis, Endothelial dysfunction, Cell biology
References
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- Transcription and epigenetics
- Podocyte vascular endothelial growth factor (Vegf164) overexpression causes severe nodular glomerulosclerosis in a mouse model of type 1 diabetes
Cited by
- Characterising COVID-19 as a Viral Clotting Fever: A Mixed-Methods Scoping Review
- Molecular Mechanisms in Early Diabetic Kidney Disease: Glomerular Endothelial Cell Dysfunction
- Machine perfused donor kidneys as a source of human renal endothelial cells.
- Glomerular Endothelial Cell Crosstalk With Podocytes in Diabetic Kidney Disease
- Therapeutic trials in adult FSGS: lessons learned and the road forward
- Interplay between extracellular matrix components and cellular and molecular mechanisms in kidney fibrosis.
- Serum Albumin in Health and Disease: Esterase, Antioxidant, Transporting and Signaling Properties
- Vascular Endothelial Cells: Heterogeneity and Targeting Approaches
- Serum free sulfhydryl status associates with new-onset chronic kidney disease in the general population
- Targeted delivery of celastrol to glomerular endothelium and podocytes for chronic kidney disease treatment
- Minimal Change Disease Is Associated With Endothelial Glycocalyx Degradation and Endothelial Activation
- Integrative Role of Albumin: Evolutionary, Biochemical and Pathophysiological Aspects
- Molecular Mechanisms of Proteinuria in Minimal Change Disease
- Heparanase promotes endothelial-to-mesenchymal transition in diabetic glomerular endothelial cells through mediating ERK signaling
- Cyclocarya paliurus triterpenoids attenuate glomerular endothelial injury in the diabetic rats via ROCK pathway.
- Astragaloside IV Improves the Barrier Damage in Diabetic Glomerular Endothelial Cells Stimulated by High Glucose and High Insulin
- Vascular Permeability in Diseases
- Flavonoids in Treatment of Chronic Kidney Disease
- Therapeutic Implications of Ferroptosis in Renal Fibrosis
- Doxycycline can reduce glycocalyx shedding by inhibiting matrix metalloproteinases in patients undergoing cardiopulmonary bypass: A randomized controlled trial.
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