Mammalian autophagy: core molecular machinery and signaling regulation
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Summary
Recent advances in identifying and understanding the core molecular machinery and signaling pathways that are involved in mammalian autophagy are highlighted.
- Type
- review
- Published
- 2009-12-23
- Cited by
- 2,008
- References
- 58
- Access
- Open access
- OpenAlex
- https://openalex.org/W1975915706
- Semantic Scholar
- https://api.semanticscholar.org/CorpusID:22336674
Keywords
Autophagy, Biology, Cell biology, Neurodegeneration, Autophagosome
References
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- Distinct regulation of autophagic activity by Atg14L and Rubicon associated with Beclin 1- phosphatidylinositol 3-kinase complex
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- Autophagosome formation: core machinery and adaptations
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- The molecular machinery of autophagy: unanswered questions
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- p53: The Janus of autophagy?
- Control of macroautophagy by calcium, calmodulin-dependent kinase kinase-beta, and Bcl-2.
- TSC2 is phosphorylated and inhibited by Akt and suppresses mTOR signalling
- FoxO3 controls autophagy in skeletal muscle in vivo.
- A novel, human Atg13 binding protein, Atg101, interacts with ULK1 and is essential for macroautophagy
- The Atg12-Atg5 Conjugate Has a Novel E3-like Activity for Protein Lipidation in Autophagy*
Cited by
- Crosstalk Between Apoptosis and Autophagy : BH3 Mimetics Activate Multiple Pro-Autophagic Pathways
- Drug Resistance Mechanisms to Gamma-secretase Inhibitors in Human Colon Cancer Cells
- Cell biology and immunology of Listeria monocytogenes infections: novel insights
- Impact of the Autophagy Machinery on Hepatitis C Virus Infection
- Autophagy in Pancreatic Cancer
- Inducer of heme oxygenase‐1 cobalt protoporphyrin accelerates autophagy and suppresses oxidative damages during lipopolysaccharide treatment in rat liver
- The scaffold protein EPG-7 links cargo–receptor complexes with the autophagic assembly machinery
- Polyamine depletion inhibits the autophagic response modulating Trypanosoma cruzi infectivity
- Autophagy Paradox and Ceramide
- Cathepsin S-mediated autophagic flux in tumor-associated macrophages accelerate tumor development by promoting M2 polarization
- ATG5 can regulate p53 expression and activation
- Autophagy gene Atg16l1 prevents lethal T cell alloreactivity mediated by dendritic cells
- miR-143 inhibits cell proliferation by targeting autophagy-related 2B in non-small cell lung cancer H1299 cells.
- Coordinated activation of AMP‐activated protein kinase, extracellular signal‐regulated kinase, and autophagy regulates phorbol myristate acetate‐induced differentiation of SH‐SY5Y neuroblastoma cells
- Mechanisms Underlying Ras-Induced Methuosis in Human Glioblastoma Cells
- Lycium barbarum Polysaccharide Improves Bipolar Pulse Current-Induced Microglia Cell Injury Through Modulating Autophagy
- Degradation of lipid droplet-associated proteins by chaperone-mediated autophagy facilitates lipolysis
- Integrated and comparative miRNA analysis of starvation-induced autophagy in mouse embryonic fibroblasts.
- Modulation of autophagy signaling with resistance exercise and protein ingestion following short-term energy deficit.
- Avermectin induced autophagy in pigeon spleen tissues.
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