Self-restrained regulation of stem cell niche activity by niche components in the Drosophila testis.
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Summary
It is found that Thickveins (Tkv, a type I receptor of the Dpp signaling pathway) in cyst stem cells (CySCs) of the testis niche prevents Dpp signaled activation outside of the niche.
- Type
- article
- Published
- 2018-07-01
- Cited by
- 13
- References
- 54
- Access
- Open access
- OpenAlex
- https://openalex.org/W2799510265
- Semantic Scholar
- https://api.semanticscholar.org/CorpusID:5015376
Keywords
Niche, Biology, Stem cell niche, Cell biology, Stem cell
References
- Nanotubes mediate niche-stem cell signaling in the Drosophila testis
- A niche maintaining germ line stem cells in the Drosophila ovary.
- Somatic support cells restrict germline stem cell self-renewal and promote differentiation
- Wnt ligands regulate Tkv expression to constrain Dpp activity in the Drosophila ovarian stem cell niche
- The relationship between the spleen colony-forming cell and the haemopoietic stem cell.
- Signaling from germ cells mediated by the rhomboid homolog stet organizes encapsulation by somatic support cells.
- Drosophila glypicans Dally and Dally-like are essential regulators for JAK/STAT signaling and Unpaired distribution in eye development
- Local BMP receptor activation at adherens junctions in the Drosophila germline stem cell niche.
- Socializing with the neighbors: stem cells and their niche.
- The torso receptor localizes as well as transduces the spatial signal specifying terminal body pattern in Drosophila
- A genome-scale shRNA resource for transgenic RNAi in Drosophila
- Control of Stem Cell Self-Renewal in Drosophila Spermatogenesis by JAK-STAT Signaling
- The Drosophila ovarian and testis stem cell niches: similar somatic stem cells and signals.
- Gbb/Bmp signaling is essential for maintaining germline stem cells and for repressing bam transcription in the Drosophila testis
- chinmo is a functional effector of the JAK/STAT pathway that regulates eye development, tumor formation and stem cell self-renewal in Drosophila
- Local signaling within stem cell niches: insights from Drosophila
- Stem Cell Self-Renewal Specified by JAK-STAT Activation in Response to a Support Cell Cue
- Regulation of stem cell maintenance and transit amplifying cell proliferation by tgf-beta signaling in Drosophila spermatogenesis.
- TGFbeta receptor saxophone non-autonomously regulates germline proliferation in a Smox/dSmad2-dependent manner in Drosophila testis.
- magu is required for germline stem cell self-renewal through BMP signaling in the Drosophila testis
Cited by
- Ectopic germ cells can induce niche-like enwrapment by neighboring body wall muscle
- Ectopic Dpp signaling promotes stem cell competition through EGFR signaling in the Drosophila testis
- Precursor RNA processing 3 is required for male fertility, and germline stem cell self-renewal and differentiation via regulating spliceosome function in Drosophila testes
- Examining the Roles of the Receptor Tyrosine Kinase PVR and the Bone Morphogenic Protein Receptor Thickvein in Regulating Self-Renewal and Division Frequency in the Cyst Stem Cells of the Drosophila Testis Niche
- Heparan sulfate negatively regulates intestinal stem cell proliferation in Drosophila adult midgut
- Self-limiting stem-cell niche signaling through degradation of a stem-cell receptor
- Somatic CG6015 mediates cyst stem cell maintenance and germline stem cell differentiation via EGFR signaling in Drosophila testes
- dRTEL1 is essential for the maintenance of Drosophila male germline stem cells
- Bone Morphogenetic Protein (BMP) signaling regulates germline stem cell self-renewal in the newly formed Drosophila testis stem cell niche
- Novel intrinsic factor Yun maintains female germline stem cell fate through Thickveins
- Single-cell RNA sequencing reveals cell landscape following antimony exposure during spermatogenesis in Drosophila testes
- A regulatory loop of JAK/STAT signalling and its downstream targets represses cell fate conversion and maintains male germline stem cell niche homeostasis
- Wnt6 is required for germline stem cell self-renewal and differentiation via regulating adhesion junction and ERK signaling in Drosophila testis
- A feedforward loop between JAK/STAT downstream target p115 and STAT in germline stem cells
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