Analyzing DNA Methylation patterns during tumor evolution
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Summary
A comprehensive computational methodology to thoroughly analyze DNA methylation patterns during tumor evolution based on bisulfite converted sequencing data, including intra-tumor methylation heterogeneity is described.
- Type
- article
- Published
- 2018-01-01
- Cited by
- 2
- References
- 39
- Access
- Open access
- OpenAlex
- https://openalex.org/W2794301847
- Semantic Scholar
- https://api.semanticscholar.org/CorpusID:24696878
Keywords
Epigenomics, DNA methylation, Epigenome, Epigenetics, Methylated DNA immunoprecipitation
References
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- CpG island hypermethylation and tumor suppressor genes: a booming present, a brighter future
- Epigenetic polymorphism and the stochastic formation of differentially methylated regions in normal and cancerous tissues
- Epigenomic evolution in diffuse large B-cell lymphomas
- DNA methylation signatures define molecular subtypes of diffuse large B-cell lymphoma.
- BS Seeker: precise mapping for bisulfite sequencing
- DNA methylation profiles in diffuse large B-cell lymphoma and their relationship to gene expression status
- Concepts in solid tumor evolution
- DNA methylation prevents CTCF-mediated silencing of the oncogene BCL6 in B cell lymphomas
- An integrated ChIP-seq analysis platform with customizable workflows
- Gene Ontology: tool for the unification of biology
- A library of gene expression signatures to illuminate normal and pathological lymphoid biology
- Reduced representation bisulfite sequencing for comparative high-resolution DNA methylation analysis
- KEGG as a reference resource for gene and protein annotation
- Cancer epigenetics: from mechanism to therapy.
- Analysis of the platypus genome suggests a transposon origin for mammalian imprinting
- Dynamic evolution of clonal epialleles revealed by methclone
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