Genetic Risk Stratification and Prevention of CAD: An Idea Whose Time Is Now.
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Summary
An international collaboration was established to analyze and perform genome-wide association studies for CAD with a sample size of over 200000 cases and controls, referred to as the Coronary Artery Disease Genome-Wide Replication and Meta-Analysis (CARDIoGRAM) consortium.
- Type
- article
- Published
- 2017-12-01
- Cited by
- 2
- References
- 14
- Access
- Open access
- OpenAlex
- https://openalex.org/W2754085950
- Semantic Scholar
- https://api.semanticscholar.org/CorpusID:20281566
Keywords
Coronary artery disease, Brugada syndrome, Genome-wide association study, Genetics, Medical genetics
References
- Secretory Phospholipase A2-IIA and Cardiovascular Disease
- Prevalence, impact, and predictive value of detecting subclinical coronary and carotid atherosclerosis in asymptomatic adults: the BioImage study.
- Improvement in Prediction of Coronary Heart Disease Risk over Conventional Risk Factors Using SNPs Identified in Genome-Wide Association Studies
- Assessment of the value of a genetic risk score in improving the estimation of coronary risk
- A Novel Genetic Approach to Investigate the Role of Plasma Secretory Phospholipase A2 (sPLA2)-V Isoenzyme in Coronary Heart Disease: A Modified Mendelian Randomization Analysis Using PLA2G5 Expression Levels
- Genetic Risk, Coronary Heart Disease Events, and the Clinical Benefit of Statin Therapy
- Genomic prediction of coronary heart disease
- Clinical Utility of Multimarker Genetic Risk Scores for Prediction of Incident Coronary Heart Disease: A Cohort Study Among Over 51 000 Individuals of European Ancestry
- Genetic Risk, Adherence to a Healthy Lifestyle, and Coronary Disease
- Multiethnic Exome-Wide Association Study of Subclinical Atherosclerosis
- Genetics and Genomics of Single-Gene Cardiovascular Diseases: Common Hereditary Cardiomyopathies as Prototypes of Single-Gene Disorders
- Genetics: Implications for Prevention and Management of Coronary Artery Disease.
- Polygenic risk score identifies subgroup with higher burden of atherosclerosis and greater relative benefit from statin therapy in the primary prevention setting
- Clonal hematopoiesis and risk for atherosclerotic cardiovascular disease
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