Stromal expression of Jagged 1 promotes colony formation by fetal hematopoietic progenitor cells.
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Summary
Results obtained in vitro table Jagged 1 as a candidate regulator of stem cell fate in the context of stromal microenvironments in vivo are obtained.
- Type
- article
- Published
- 1998-09-01
- Cited by
- 160
- References
- 39
- OpenAlex
- https://openalex.org/W2751246398
- Semantic Scholar
- https://api.semanticscholar.org/CorpusID:42609614
Keywords
Stromal cell, Progenitor cell, Biology, CD34, Haematopoiesis
References
- Transient and restricted expression during mouse embryogenesis of Dll1, a murine gene closely related to Drosophila Delta.
- A homolog of Drosophila Notch expressed during mammalian development.
- Mutations in the human Jagged1 gene are responsible for Alagille syndrome
- Jagged: a mammalian ligand that activates Notch1.
- Characterization of the first definitive hematopoietic stem cells in the AGM and liver of the mouse embryo.
- Alagille syndrome is caused by mutations in human Jagged1, which encodes a ligand for Notch1
- Hematopoietic activity of a stromal cell transmembrane protein containing epidermal growth factor-like repeat motifs.
- Jagged2: a serrate-like gene expressed during rat embryogenesis.
- A new preadipose cell line derived from newborn mouse calvaria can promote the proliferation of pluripotent hemopoietic stem cells in vitro
- Emergence of multipotent hemopoietic cells in the yolk sac and paraaortic splanchnopleura in mouse embryos, beginning at 8.5 days postcoitus.
- TAN-1, the human homolog of the Drosophila notch gene, is broken by chromosomal translocations in T lymphoblastic neoplasms.
- Raf‐1 Protein is Required for Growth Factor‐Induced Proliferation of Primitive Hematopoietic Progenitors Stimulated with Synergistic Combinations of Cytokines
- Intrinsic activity of the Lin-12 and Notch intracellular domains in vivo.
- The human homolog of rat Jagged1 expressed by marrow stroma inhibits differentiation of 32D cells through interaction with Notch1.
- Notch Activity Influences the αβ versus γδ T Cell Lineage Decision
- Microenvironmental regulation of hematopoietic stem cells
- An activated Notch receptor blocks cell-fate commitment in the developing Drosophila eye
- The novel Notch homologue mouse Notch 3 lacks specific epidermal growth factor-repeats and is expressed in proliferating neuroepithelium.
- An activated form of Notch influences the choice between CD4 and CD8 T cell lineages.
- Functional characterization of two stromal cell lines that support B lymphopoiesis.
Cited by
- Notch signalling via RBP‐J promotes myeloid differentiation
- Stromal cell-dependent ex vivo expansion of human cord blood progenitors and augmentation of transplantable stem cell activity
- Membrane-bound Delta-4 Notch ligand reduces the proliferative activity of primitive human hematopoietic CD34+CD38low cells while maintaining their LTC-IC potential
- In vitro expansion of long‐term repopulating hematopoietic stem cells in the presence of immobilized Jagged‐1 and early acting cytokines
- Inactivation of Notch signaling in the renal collecting duct causes nephrogenic diabetes insipidus in mice.
- Effective expansion of engrafted human hematopoietic stem cells in bone marrow of mice expressing human Jagged1.
- Monocytes express high amounts of Notch and undergo cytokine specific apoptosis following interaction with the Notch ligand, Delta-1.
- The role of the tumor microenvironment in hematological malignancies and implication for therapy.
- Molecular Characterization of the T(4;9)12Gso Mutation and Analysis of the Associated Fitness, Skeletal, and Lymphoproliferative Phenotypes
- Induction of pluripotency.
- Notch as a mediator of cell fate determination in hematopoiesis: evidence and speculation.
- Homing of hematopoietic progenitor cells to the bone marrow
- Ectopic expression of Delta4 impairs hematopoietic development and leads to lymphoproliferative disease.
- Notch Signaling Pathway Activation in Normal and Hyperglycemic Rats Differs in the Stem Cells of Visceral and Subcutaneous Adipose Tissue
- Notch signalling pathway in murine embryonic stem cell derived haematopoiesis
- Normal and Leukemic Hematopoiesis
- To be or notch to be
- Notch signaling in the regulation of stem cell self-renewal and differentiation.
- Notch Signaling Enhances Survival and Alters Differentiation of 32D Myeloblasts1
- Células madre hematopoyéticas, generalidades y vías implicadas en sus mecanismos de auto-renovación
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