Risks of Breast, Ovarian, and Contralateral Breast Cancer for BRCA1 and BRCA2 Mutation Carriers
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Summary
To estimate age-specific risks of breast, ovarian, and contralateral breast cancer for mutation carriers and to evaluate risk modification by family cancer history and mutation location, a large cohort study recruited in 1997-2011 provides estimates of cancer risk based on BRCA1 and BRCa2 mutation carrier status.
- Type
- article
- Published
- 2017-06-20
- Cited by
- 2,644
- References
- 34
- Access
- Open access
- OpenAlex
- https://openalex.org/W2627871710
- Semantic Scholar
- https://api.semanticscholar.org/CorpusID:205093245
Keywords
Medicine, Breast cancer, Oncology, Ovarian cancer, Mutation
References
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- Identification of a BRCA2-Specific Modifier Locus at 6p24 Related to Breast Cancer Risk
Cited by
- The role of transvaginal ultrasound in screening for ovarian cancer
- Accurate detection and quantification of epigenetic and genetic second hits in BRCA1 and BRCA2-associated hereditary breast and ovarian cancer reveals multiple co-acting second hits.
- Electronically ascertained extended pedigrees in breast cancer genetic counseling
- Benchmarking of a checklist for the identification of familial risk for breast and ovarian cancers in a prospective cohort
- Comprehensive genomic characterization of breast tumors with BRCA1 and BRCA2 mutations
- Epithelial ovarian cancer.
- Risikoadaptierte Betreuungskonzepte bei Mammakarzinom-Hochrisikopatientinnen
- Abstract DPOC-005: #OVARIANCANCER: USING SOCIAL MEDIA TO FACILITATE HEALTH COMMUNICATION
- BRCA population screening for predicting breast cancer: for or against?
- The subject and power of bioethics
- Les défis du séquençage à haut débit dans l'exploration génétique des cancers du sein et de l'ovaire.
- Fertility and pregnancy issues in BRCA-mutated breast cancer patients.
- Genetics: BRCA-mutant breast/ovarian cancer revealed
- Risk of uterine cancer for BRCA1 and BRCA2 mutation carriers.
- Genetic testing in women with breast cancer: implications for treatment
- Impact of Etoposide on BRCA1 Expression in Various Breast Cancer Cell Lines
- Mutations in Context: Implications of BRCA Testing in Diverse Populations
- The expected benefit of preventive mastectomy on breast cancer incidence and mortality in BRCA mutation carriers, by age at mastectomy
- Reproductive potential and performance of fertility preservation strategies in BRCA-mutated breast cancer patients
- Genetic epidemiology of ovarian cancer and prospects for polygenic risk prediction.
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