Risk of uterine cancer for BRCA1 and BRCA2 mutation carriers.
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Summary
The findings of this multicentre, prospective cohort study are consistent with those from most other reports and do not support routine risk-reducing hysterectomy for BRCA1 and BRCa2 mutation carriers.
- Type
- article
- Published
- 2017-10-01
- Cited by
- 35
- References
- 43
- OpenAlex
- https://openalex.org/W2742842577
- Semantic Scholar
- https://api.semanticscholar.org/CorpusID:7217833
Keywords
Medicine, Uterine cancer, Breast cancer, Population, Cancer
References
- Endometrium is not the primary site of origin of pelvic high-grade serous carcinoma in BRCA1 or BRCA2 mutation carriers
- kConFab: a research resource of Australasian breast cancer families
- Analysis of cancer risk and BRCA1 and BRCA2 mutation prevalence in the kConFab familial breast cancer resource
- National Cancer Institute of Canada Clinical Trials Group MAP.3 Trial: evaluation of exemestane to prevent breast cancer in postmenopausal women.
- Comparison of uterine malignancies that develop during and following tamoxifen therapy.
- Surgical approach to hysterectomy for benign gynaecological disease.
- Role of prophylactic hysterectomy in patients at high risk for hereditary cancers.
- Etiologic Heterogeneity in Endometrial Cancer: Evidence from a Gynecologic Oncology Group Trial
- Relationship between tamoxifen use and high risk endometrial cancer histologic types.
- Predictors of participation in clinical and psychosocial follow-up of the kConFab breast cancer family cohort
- Cancer Incidence in BRCA1 mutation carriers.
- New Views on the Pathogenesis of High-grade Pelvic Serous Carcinoma with Suggestions for Advancing Future Research
- Abdominal versus laparoscopic hysterectomies for benign diseases: evaluation of morbidity and mortality among 465,798 cases
- The incidence of endometrial cancer in women with BRCA1 and BRCA2 mutations: an international prospective cohort study.
- THE CELL OF ORIGIN OF OVARIAN EPITHELIAL TUMORS
- [Indications for prophylactic hysterectomy].
- Anastrozole for prevention of breast cancer in high-risk postmenopausal women (IBIS-II): an international, double-blind, randomised placebo-controlled trial.
- Breast Cancer After Use of Estrogen Plus Progestin and Estrogen Alone
- Breast and Ovarian Cancer Risks Due to Inherited Mutations in BRCA1 and BRCA2
- New insights into the pathogenesis of serous ovarian cancer and its clinical impact.
Cited by
- Genetic testing in women with breast cancer: implications for treatment
- Cancer Risk-Reducing Opportunities in Gynecologic Surgery.
- Risk-reducing bilateral salpingo-oophorectomy in women with BRCA1 or BRCA2 mutations.
- Uterine cancer in Jewish Israeli BRCA1/2 mutation carriers
- Hormone replacement therapy after risk reducing salpingo-oophorectomy in patients with BRCA1 or BRCA2 mutations; a systematic review of risks and benefits.
- Germline BRCA-Associated Endometrial Carcinoma Is a Distinct Clinicopathologic Entity
- Two distinct tumorigenic processes in endometrial endometrioid adenocarcinoma.
- Endometrial cancer prevention in high-risk women.
- Uterine cancer in breast cancer survivors: a systematic review
- BRCA1 and BRCA2 pathogenic variant carriers and endometrial cancer risk: A cohort study
- Cancer Surveillance in Healthy Carriers of Germline Pathogenic Variants in BRCA1/2: A Review of Secondary Prevention Guidelines
- Postmenopausal hormone therapy in BRCA gene mutation carriers: to whom and which?
- Hereditary Predisposition to Prostate Cancer: From Genetics to Clinical Implications
- Endometrial cancer in germline BRCA mutation carriers: a systematic review and meta-analysis.
- Should the risk for uterine cancer influence decision making for prophylactic hysterectomy in BRCA1/2 mutated patients- a systematic review and meta-analysis.
- Endometrial Cancer Risk in Women With Germline BRCA1 or BRCA2 Mutations: Multicenter Cohort Study
- Genetics of Breast and Ovary Cancers Associated with Hereditary Cancers and their Clinical Management
- British Gynaecological Cancer Society (BGCS) uterine cancer guidelines: Recommendations for practice.
- Hereditary gynecologic tumors and precision cancer medicine
- Executive Summary of the Uterine Cancer Evidence Review Conference
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