Urinary metabolomics study on the protective role of Orthosiphon stamineus in Streptozotocin induced diabetes mellitus in rats via 1H NMR spectroscopy
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Summary
The results of this study validated the ethnopharmacological use of OS in diabetes and unveiled the biochemical and metabolic mechanisms involved.
- Type
- article
- Published
- 2017-05-25
- Cited by
- 32
- References
- 34
- Access
- Open access
- OpenAlex
- https://openalex.org/W2617402382
- Semantic Scholar
- https://api.semanticscholar.org/CorpusID:8654185
Keywords
Diabetes mellitus, Metabolomics, Medicine, Glibenclamide, Streptozotocin
References
- Metabolic alteration in obese diabetes rats upon treatment with Centella asiatica extract.
- Use of complementary and alternative medicine among people living with diabetes: literature review.
- MetaboAnalyst 3.0—making metabolomics more meaningful
- Metabolomics approaches for discovering biomarkers of drug-induced hepatotoxicity and nephrotoxicity.
- Antidiabetic Properties and Mechanism of Action of Orthosiphon stamineus Benth Bioactive Sub-fraction in Streptozotocin-induced Diabetic Rats
- Studies on diuretic and hypouricemic effects of Orthosiphon stamineus methanol extracts in rats.
- Global prevalence of diabetes: estimates for the year 2000 and projections for 2030.
- NMR-based metabonomic study of Chinese medicine Gegen Qinlian Decoction as an effective treatment for type 2 diabetes in rats
- Orthosiphon stamineus: Traditional Uses, Phytochemistry, Pharmacology, and Toxicology
- Phytochemical and pharmacological studies on Orthosiphon stamineus Benth. (Lamiaceae) hydroalcoholic extracts.
- Anabolic response of some tissues to diabetes.
- Classification and correlation of St. John's wort extracts by nuclear magnetic resonance spectroscopy, multivariate data analysis and pharmacological activity.
- Metabolomic and lipidomic study of the protective effect of Chaihuang-Yishen formula on rats with diabetic nephropathy.
- OA07.03. Randomized, double-blind, double-dummy trial of myrrh, chamomile, coffee charcoal compared to mesalazine in maintaining remission in ulcerative colitis
- Unraveling Biochemical Pathways Affected by Mitochondrial Dysfunctions Using Metabolomic Approaches
- Recent and potential developments of biofluid analyses in metabolomics.
- Effects of Orthosiphon stamineus aqueous extract on plasma glucose concentration and lipid profile in normal and streptozotocin-induced diabetic rats.
- Probabilistic quotient normalization as robust method to account for dilution of complex biological mixtures. Application in 1H NMR metabonomics.
- Global Diabetes Survey--an annual report on quality of diabetes care.
- Potent α-glucosidase and α-amylase inhibitory activities of standardized 50% ethanolic extracts and sinensetin from Orthosiphon stamineus Benth as anti-diabetic mechanism
Cited by
- Orthosiphon stamineus Benth. is an Outstanding Food Medicine: Review of Phytochemical and Pharmacological Activities
- Fasting serum α‑hydroxybutyrate and pyroglutamic acid as important metabolites for detecting isolated post-challenge diabetes based on organic acid profiles.
- Arabinoxylan Attenuates Type 2 Diabetes by Improvement of Carbohydrate, Lipid, and Amino Acid Metabolism
- Effects of Clinacanthus nutans leaf extract on lipopolysaccharide -induced neuroinflammation in rats: A behavioral and 1H NMR-based metabolomics study
- Determination of progesterone compounds in the crude methanol extract of benalu duku leaves
- Orthosiphon stamineus Benth (Uses and Bioactivities)
- Urinary metabolomics analysis reveals the anti-diabetic effect of stachyose in high-fat diet/streptozotocin-induced type 2 diabetic rats.
- Evaluating Traditional Chinese Medicine and Herbal Products for the Treatment of Gestational Diabetes Mellitus
- Detection of Early Disease Risk Factors Associated with Metabolic Syndrome: A New Era with the NMR Metabolomics Assessment
- Psychopharmacological effects of riparin III from Aniba riparia (Nees) Mez. (Lauraceae) supported by metabolic approach and multivariate data analysis
- The application of metabolomics in investigating anti-diabetic activity of medicinal plants.
- Serum metabolomics analysis of the intervention effect of whole grain oats on insulin resistance induced by high-fat diet in rats.
- Serum Metabolomics Profiling of Commercially Mixed Functional Foods—Effects in Beta-Amyloid Induced Rats Measured Using 1H NMR Spectroscopy
- The Prediction of Active Ingredients and Polypharmacological Mechanisms of Orthosiphon stamineus Benth. (Lamiaceae) of Dai medicine based on Network Pharmacology
- Herbalism for Modern Obstetrics.
- Investigation of metabolites produced by Magnaporthe oryzae during appressorium development using 1H NMR metabolomics approach
- A Systematic Review of Orthosiphon stamineus Benth. in the Treatment of Diabetes and Its Complications
- Using Metabolomics in Diabetes Management with Traditional Chinese Medicine: A Review.
- Metabolomics based biomarker identification of anti-diabetes and anti-obesity properties of Malaysian herbs
- Potential Therapeutic Mechanism of Traditional Chinese Medicine on Diabetes in Rodents: A Review from an NMR-Based Metabolomics Perspective
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