Metabolic alteration in obese diabetes rats upon treatment with Centella asiatica extract.
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Summary
A long-term treatment of obese diabetic rats with CA extract could reverse the glucose and lipid levels, as well as the tricarboxylic acid cycle and amino acid metabolic disorders, back towards normal states.
- Type
- article
- Published
- 2016-03-02
- Cited by
- 83
- References
- 40
- Access
- Open access
- OpenAlex
- https://openalex.org/W26775274
- Semantic Scholar
- https://api.semanticscholar.org/CorpusID:7013961
Keywords
Medicine
References
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- Anti-hyperglycemic activity of Centella asiatica is partly mediated by carbohydrase inhibition and glucose-fiber binding
- Asiatic acid prevents lipid peroxidation and improves antioxidant status in rats with streptozotocin-induced diabetes
- Metabolomic studies of experimental diabetic urine samples by 1H NMR spectroscopy and LC/MS method
- Efficacy of asiatic acid, a pentacyclic triterpene on attenuating the key enzymes activities of carbohydrate metabolism in streptozotocin-induced diabetic rats.
- Inhibitory effects of ursolic acid on hepatic polyol pathway and glucose production in streptozotocin-induced diabetic mice.
- Stress and the inflammatory process: a major cause of pancreatic cell death in type 2 diabetes
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- Antidiabetic and antihyperlipidemic activity of asiatic acid in diabetic rats, role of HMG CoA: in vivo and in silico approaches.
- Comparison of Partial Least Squares and Artificial Neural Network for the prediction of antioxidant activity in extract of pegaga (centella) varieties from 1H Nuclear Magnetic Resonance spectroscopy.
- Ethnobotanical survey of medicinal plants used by Bapedi healers to treat diabetes mellitus in the Limpopo Province, South Africa.
- NMR-based metabonomic study of Chinese medicine Gegen Qinlian Decoction as an effective treatment for type 2 diabetes in rats
- Creatine metabolism and the urea cycle.
Cited by
- NMR based Pharmaco-metabolomics: An efficient and agile tool for therapeutic evaluation of Traditional Herbal Medicines
- Metabolic and biochemical changes in streptozotocin induced obese-diabetic rats treated with Phyllanthus niruri extract.
- Anti-Diabetic Activity and Metabolic Changes Induced by Andrographis paniculata Plant Extract in Obese Diabetic Rats
- Nephroprotective effect of Rudgea viburnoides (Cham.) Benth leaves on gentamicin-induced nephrotoxicity in rats.
- Urinary metabolomics study on the protective role of Orthosiphon stamineus in Streptozotocin induced diabetes mellitus in rats via 1H NMR spectroscopy
- Metabolic Effect of 1-Deoxynojirimycin from Mulberry Leaves on db/db Diabetic Mice Using Liquid Chromatography-Mass Spectrometry Based Metabolomics.
- A review on medicinal properties of Centella asiatica
- Application of BATMAN and BAYESIL for quantitative 1H-NMR based metabolomics of urine: discriminant analysis of lean, obese, and obese-diabetic rats
- Effect of Ipomoea aquatica ethanolic extract in streptozotocin (STZ) induced diabetic rats via1H NMR-based metabolomics approach.
- Centella asiatica ameliorates diabetes-induced stress in rat tissues via influences on antioxidants and inflammatory cytokines.
- Metabolomic analysis and biochemical changes in the urine and serum of streptozotocin-induced normal- and obese-diabetic rats
- Anti-Inflammatory Effect of Centella asiatica Extract on Prevented Aortic Intima-Media Thickening in Diabetic Rats
- Plasma and urine metabolite profiling reveals the protective effect of Clinacanthus nutans in an ovalbumin‐induced anaphylaxis model: 1H‐NMR metabolomics approach
- Hematological, Biochemical, Histopathological and 1H-NMR Metabolomics Application in Acute Toxicity Evaluation of Clinacanthus nutans Water Leaf Extract
- Effects of Centella asiatica on skeletal muscle structure and key enzymes of glucose and glycogen metabolism in type 2 diabetic rats.
- Protective Effects of Centella asiatica on Cognitive Deficits Induced by D-gal/AlCl3 via Inhibition of Oxidative Stress and Attenuation of Acetylcholinesterase Level
- Antidiabetic effect of Centella asiatica extract (whole plant) in streptozotocin nicotinamide-induced diabetic rats
- Antidiabetic Potential of Medicinal Plants and Their Active Components
- Application of quantitative spectral deconvolution 1H NMR (qsd-NMR) in the simultaneous quantitative determination of creatinine and metformin in human urine
- Analysis of urinary metabolic alteration in type 2 diabetic rats treated with metformin using the metabolomics of quantitative spectral deconvolution 1H NMR spectroscopy
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