Global Metabolomic Profiling of Mice Brains following Experimental Infection with the Cyst-Forming Toxoplasma gondii
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Summary
Findings indicate that global metabolomics adopted in this study is a sensitive approach for detecting metabolic alterations in T. gondii-infected mice and generated a comparative metabolic profile of brain tissue distinguishing infected from non- Infected host.
- Type
- article
- Published
- 2015-10-02
- Cited by
- 41
- References
- 49
- Access
- Open access
- OpenAlex
- https://openalex.org/W1854805732
- Semantic Scholar
- https://api.semanticscholar.org/CorpusID:15536719
Keywords
Metabolomics, Metabolic pathway, Toxoplasma gondii, Biology, Metabolism
References
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- Visualization of GC/TOF-MS-based metabolomics data for identification of biochemically interesting compounds using OPLS class models.
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- Role of Acetyl‐l‐Carnitine in Rat Brain Lipogenesis: Implications for Polyunsaturated Fatty Acid Biosynthesis
- IMP Dehydrogenase from the Protozoan Parasite Toxoplasma gondii
- Increased cerebellar Purkinje cell numbers in mice overexpressing a human Bcl‐2 transgene
Cited by
- Proteomic Profiling of Mouse Liver following Acute Toxoplasma gondii Infection
- Toxoplasma gondii infection and schizophrenia: an inter-kingdom communication perspective
- Metabolomic Profiling of Mice Serum during Toxoplasmosis Progression Using Liquid Chromatography-Mass Spectrometry
- The known and missing links between Toxoplasma gondii and schizophrenia
- Global iTRAQ-based proteomic profiling of Toxoplasma gondii oocysts during sporulation.
- Brain metabolomic profiling of eastern honey bee (Apis cerana) infested with the mite Varroa destructor
- Profiling of the perturbed metabolomic state of mouse spleen during acute and chronic toxoplasmosis
- Serum Metabolic Profiling of Oocyst-Induced Toxoplasma gondii Acute and Chronic Infections in Mice Using Mass-Spectrometry
- Computational Systems Biology of Metabolism in Infection.
- Hepatic Metabolomics Investigation in Acute and Chronic Murine Toxoplasmosis
- Metabolomics applied to maternal and perinatal health: a review of new frontiers with a translation potential
- Label-free characterization of biochemical changes within human cells under parasite attack using synchrotron based micro-FTIR
- Immunometabolism: an overview and therapeutic prospects in autoimmune diseases.
- Fit for purpose? A metascientific analysis of metabolomics data in public repositories
- Comparative Metabonomic Investigations of Schistosoma japonicum From SCID Mice and BALB/c Mice: Clues to Developmental Abnormality of Schistosome in the Immunodeficient Host
- Metabolomic signature of mouse cerebral cortex following Toxoplasma gondii infection
- Disease Tolerance in Toxoplasma Infection
- Comparative serum metabolomics between SCID mice and BALB/c mice with or without Schistosoma japonicum infection: clues to the abnormal growth and development of schistosome in SCID mice.
- Induction and measurement of the early stage of a host‐parasite interaction using a combined optical trapping and Raman microspectroscopy system
- Enhancement of glucose homeostasis through the PI3K/Akt signaling pathway by dietary with Agaricus blazei Murrill in STZ‐induced diabetic rats
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