Design and synthesis of near-infrared fluorescence-enhancement probes for the cancer-specific enzyme hNQO1
Explore this paper's citation graph
Summary
A new NIR fluorescent probe based on cleavage of ester and intramolecular charge transfer effect showed fast-response property toward hNQO1 for real-time enzymatic assay in vitro, implying that the new probe could serve as potentially efficient tools for detection of endogenous hNZO1 in living animals.
- Type
- article
- Published
- 2017-08-01
- Cited by
- 33
- References
- 29
- OpenAlex
- https://openalex.org/W2609678068
- Semantic Scholar
- https://api.semanticscholar.org/CorpusID:91011796
Keywords
Fluorescence, Cancer cell, In vivo, In vitro, Chemistry
References
- A DT-diaphorase responsive theranostic prodrug for diagnosis, drug release monitoring and therapy.
- The Therapeutic Potential of Cystathionine β-Synthetase/Hydrogen Sulfide Inhibition in Cancer
- Pro-fluorogenic Reductase Substrate for Rapid, Selective, and Sensitive Visualization and Detection of Human Cancer Cells that Overexpress NQO1
- NAD(P)H:quinone acceptor oxidoreductase 1 (NQO1), a multifunctional antioxidant enzyme and exceptionally versatile cytoprotector
- Near-infrared spectroscopy and hyperspectral imaging: non-destructive analysis of biological materials.
- Near Infrared Fluorescence Imaging for early detection, monitoring and improved intervention of diseases involving the joint
- Advancing biomedical imaging
- Environmentally Robust Rhodamine Reporters for Probe-based Cellular Detection of the Cancer-linked Oxidoreductase hNQO1.
- Recent conjugation strategies of small organic fluorophores and ligands for cancer-specific bioimaging.
- Detection and Cellular Imaging of Human Cancer Enzyme Using a Turn-On, Wavelength-Shiftable, Self-Immolative Profluorophore
- A unique approach to development of near-infrared fluorescent sensors for in vivo imaging.
- Mitochondria-targeted aggregation induced emission theranostics: crucial importance of in situ activation
- A highly selective and sensitive near-infrared fluorescent probe for imaging of hydrogen sulphide in living cells and mice
- Critical Review Upon the Role and Potential of Fluorescence and Near-Infrared Imaging and Absorption Spectroscopy in Cancer Related Cells, Serum, Saliva, Urine and Tissue Analysis.
- Recent Development of Chemosensors Based on Cyanine Platforms.
- Oxidoreductase-Facilitated Visualization and Detection of Human Cancer Cells.
- Sulforaphane Regulates NFE2L2/Nrf2-Dependent Xenobiotic Metabolism Phase II and Phase III Enzymes Differently in Human Colorectal Cancer and Untransformed Epithelial Colon Cells
- Rational construction of probes rendering ratiometric response to the cancer-specific enzyme NQO1
- From tumour heterogeneity to advances in precision treatment of colorectal cancer
- An efficient two-photon fluorescent probe for human NAD(P)H:quinone oxidoreductase (hNQO1) detection and imaging in tumor cells.
Cited by
- Design and synthesis of NBD-S-dye dyads for fluorescently discriminative detection of biothiols and Cys/Hcy
- Fluorescein-Inspired Near-Infrared Chemodosimeter for Luminescence Bioimaging.
- Quinone-based fluorophores for imaging biological processes.
- Facile synthesis of green-light and large Stokes-shift emitting coumarins for bioconjugation
- A two-photon ratiometric probe for detection of hNQO1 enzyme activity in human colon tissue
- Trimethyl Lock: A Multifunctional Molecular Tool for Drug Delivery, Cellular Imaging, and Stimuli‐Responsive Materials
- A NBD-S-rhodamine dyad for dual-color discriminative imaging of biothiols and Cys/Hcy
- Recent progresses in small-molecule enzymatic fluorescent probes for cancer imaging.
- Fluorogenic probes for disease-relevant enzymes.
- Cancer-Specific Biomarker hNQO1-Activatable Fluorescent Probe for Imaging Cancer Cells In Vitro and In Vivo
- Dual-biomarker-triggered fluorescence probes for differentiating cancer cells and revealing synergistic antioxidant effects under oxidative stress
- Design and synthesis of NQO1 responsive fluorescence probe and its application in bio-imaging for cancer diagnosis.
- A Highly Sensitive Two‐Photon Ratiometric Probe for Rapid Detection of the hNQO1 Enzyme in Colon Cancer Tissue
- CO2/CH4 adsorption at high-pressure using silica-APTES aerogel as adsorbent and near infrared as a monitoring technique
- Characterization of a highly specific NQO1-activated near-infrared fluorescent probe and its application for in vivo tumor imaging
- GSH Activated Biotin-tagged Near-Infrared Probe for Efficient Cancer Imaging
- Rational Design of Ratiometric Near-Infrared Aza-BODIPY-Based Fluorescent Probe for in Vivo Imaging of Endogenous Hydrogen Peroxide
- A xanthene derivative, free or associated to nanoparticles, as a new potential agent for anticancer photodynamic therapy
- Electrochemiluminescent detection of hNQO1 and associated drug screening enabled by futile redox cycle reaction
- Iodinated xanthene-cyanine NIR dyes as potential photosensitizers for antimicrobial photodynamic therapy
Related papers
- The effects of beer on the serum enzyme activities in vivo and vitro
- A Flavone-Based Long-Wavelength Fluorescent Probe to Detect Biothiols in vitro and in vivo
- Amyloid-β Deposits Target Efficient Near-Infrared Fluorescent Probes: Synthesis, in Vitro Evaluation, and in Vivo Imaging.
- Comparison of isoproterenol-induced changes in lysosomal enzyme activity in vivo and in vitro.
- Naphthalimide-rhodamine based fluorescent probe for ratiometric sensing of cellular pH
- DNase-activatable fluorescence probes visualizing the degradation of exogenous DNA in living cells.
- An In Vivo Fluorescence Resonance Energy Transfer-Based Imaging Platform for Targeted Drug Discovery and Cancer Therapy
- Dynamic Co-Evolution of Cancer Cells and Cancer-Associated Fibroblasts: Role in Right- and Left-Sided Colon Cancer Progression and Its Clinical Relevance
- Fluorinated N,N′-Diarylureas As Novel Therapeutic Agents Against Cancer Stem Cells