Dual-biomarker-triggered fluorescence probes for differentiating cancer cells and revealing synergistic antioxidant effects under oxidative stress
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Summary
Dual-biomarker-triggered fluorescent probes were developed for simultaneous detection of the two biomarkers H2S and hNQO1 in cancer cells.
- Type
- article
- Published
- 2019-01-11
- Cited by
- 44
- References
- 78
- Access
- Open access
- OpenAlex
- https://openalex.org/W2910934865
- Semantic Scholar
- https://api.semanticscholar.org/CorpusID:85562657
Keywords
Oxidative stress, Biomarker, Fluorescence, Antioxidant, Chemistry
References
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- Selective fluorescent probes for live-cell monitoring of sulphide.
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- Pro-fluorogenic Reductase Substrate for Rapid, Selective, and Sensitive Visualization and Detection of Human Cancer Cells that Overexpress NQO1
- Identification of aldo-keto reductases as NRF2-target marker genes in human cells.
- The third gas: H2S regulates perfusion pressure in both the isolated and perfused normal rat liver and in cirrhosis
- A ratiometric fluorescent probe for rapid detection of hydrogen sulfide in mitochondria.
- A FRET-ICT dual-quenching fluorescent probe with large off-on response for H2S: synthesis, spectra and bioimaging.
- A Strategy for Dual-Analyte Luciferin Imaging: In Vivo Bioluminescence Detection of Hydrogen Peroxide and Caspase Activity in a Murine Model of Acute Inflammation
- Hydrogen sulfide-based therapeutics: exploiting a unique but ubiquitous gasotransmitter
- NAD(P)H:quinone acceptor oxidoreductase 1 (NQO1), a multifunctional antioxidant enzyme and exceptionally versatile cytoprotector
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- Hydrogen sulphide and its therapeutic potential
- Hydrogen sulfide protects neurons from oxidative stress
- Hydrogen sulfide is an endogenous stimulator of angiogenesis
Cited by
- A mitochondria-targeted red-emitting probe for imaging hydrogen sulfide in living cells and zebrafish.
- Mitochondria Targeting Fluorescent Probes Based on through Bond-Energy Transfer for Mutually Imaging Signaling Molecules H2 S and H2 O2.
- An NBD‐Based Mitochondrial Targeting Ratiometric Fluorescent Probe for Hydrogen Sulfide Detection
- Dual-quenching NBD-based fluorescent probes for separate detection of H2S and Cys/Hcy in living cells.
- Hemicyanine-based near-infrared fluorescent probe for the ultrasensitive detection of hNQO1 activity and discrimination of human cancer cells.
- Carbonyl Sulfide (COS) Donor induced protein persulfidation protects against oxidative stress.
- A novel water-soluble fluorescent probe with ultra-sensitivity over a wider pH range and its application for differentiating cancer cells from normal cells.
- A fluorescent probe for simultaneously sensing NTR and hNQO1 and distinguishing cancer cells.
- Selenosulfides Tethered to Gem-Dimethyl Esters: A Robust and Highly Versatile Framework for H₂S Probe Development.
- Hydrogen Sulfide: Emerging Role in Bladder, Kidney, and Prostate Malignancies
- Crystal structure of 3-methyl-3-(2,4,5-trimethyl-3,6-dioxocyclohexa-1,4-dien-1-yl)butanoic acid, C14H18O4
- Simultaneous imaging of mitochondrial viscosity and hydrogen peroxide in Alzheimer's disease by a single near-infrared fluorescent probe with a large Stokes shift.
- A Fast-Response Red Shifted Fluorescent Probe for Detection of H2S in Living Cells
- Curcumin-based polarity fluorescent probes: Design strategy and biological applications
- Methylene blue-based 7-nitro-1,2,3-benzoxadiazole NIR fluorescent probe triggered by H2S.
- NBD-based fluorescent probes for separate detection of cysteine and biothiols via different reactivities.
- Electrochemiluminescent detection of hNQO1 and associated drug screening enabled by futile redox cycle reaction
- Highly efficient H2S scavengers via thiolysis of positively-charged NBD amines
- A near-infrared excitation/emission fluorescent probe for imaging of endogenous cysteine in living cells and zebrafish
- Covalent-Assembly Based Fluorescent Probes for Detection of hNQO1 and Imaging in Living Cells
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