MicroRNA therapeutics: towards a new era for the management of cancer and other diseases
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Summary
Recent advances in the understanding of miRNAs in cancer and in other diseases are described and the challenge of identifying the most efficacious therapeutic candidates is discussed and a perspective on achieving safe and targeted delivery of miRNA therapeutics is provided.
- Type
- review
- Published
- 2017-02-17
- Cited by
- 4,269
- References
- 204
- OpenAlex
- https://openalex.org/W2588025094
- Semantic Scholar
- https://api.semanticscholar.org/CorpusID:22956490
Keywords
microRNA, Computational biology, Disease, Cancer, Bioinformatics
References
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Cited by
- Diagnostic and therapeutic applications of miRNA-based strategies to cancer immunotherapy
- A guide to miRNAs in inflammation and innate immune responses
- MiR-205 as predictive biomarker and adjuvant therapeutic tool in combination with trastuzumab
- The potential role of miRNAs in multiple myeloma therapy
- MicroRNA-613 promotes colon cancer cell proliferation, invasion and migration by targeting ATOH1.
- miR-632 promotes gastric cancer progression by accelerating angiogenesis in a TFF1-dependent manner
- Long Non-coding RNAs Are Central Regulators of the IL-1β-Induced Inflammatory Response in Normal and Idiopathic Pulmonary Lung Fibroblasts
- Bioengineered Let-7c Inhibits Orthotopic Hepatocellular Carcinoma and Improves Overall Survival with Minimal Immunogenicity
- Target RNA-directed microRNA degradation; which controls which?
- The untranslated regions of mRNAs in cancer
- miRNA deregulation targets specific pathways in leiomyosarcoma development: an in silico analysis
- miR-6716-5p promotes metastasis of colorectal cancer through downregulating NAT10 expression
- Pancreatic Ductal Adenocarcinoma: MicroRNAs Affecting Tumor Growth and Metastasis in Preclinical In Vivo Models
- Neutrophil-derived extracellular vesicles induce endothelial inflammation and damage through the transfer of miRNAs.
- Upregulation of miR-181a suppresses the formation of glioblastoma stem cells by targeting the Notch2 oncogene and correlates with good prognosis in patients with glioblastoma multiforme.
- miRNAs: micro-managers of anticancer combination therapies
- Exploiting Epigenetic Alterations in Prostate Cancer
- Molecular Regulation of Cellular Senescence by MicroRNAs: Implications in Cancer and Age-Related Diseases.
- Epigenetic Regulation of Telomere Maintenance for Therapeutic Interventions in Gliomas
- miR miR on the wall, who’s the most malignant medulloblastoma miR of them all?
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