The miR-200 family determines the epithelial phenotype of cancer cells by targeting the E-cadherin repressors ZEB1 and ZEB2.

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Summary

The data identify miR-200 as a powerful marker and determining factor of the epithelial phenotype of cancer cells as well as an extraordinary marker for cells that express E-cadherin but lack expression of Vimentin.

Type
article
Published
2008-04-01
Cited by
2,356
References
49
Access
Open access

Keywords

Biology, Sequence (biology), Gene, Repressor, Oligonucleotide

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