EMERGING BIOLOGICAL PRINCIPLES OF METASTASIS
Explore this paper's citation graph
Summary
The cellular and molecular mechanisms involved in metastasis are summarized, with a focus on carcinomas where the most is known, and the general principles of metastasis that have begun to emerge are highlighted.
- Type
- review
- Published
- 2017-02-01
- Cited by
- 2,710
- References
- 207
- Access
- Open access
- OpenAlex
- https://openalex.org/W2586407709
- Semantic Scholar
- https://api.semanticscholar.org/CorpusID:206562415
Keywords
Biology, Metastasis, Cancer metastasis, Cancer, Focus (optics)
References
- Metastasis: from dissemination to organ-specific colonization
- The BMP Inhibitor Coco Reactivates Breast Cancer Cells at Lung Metastatic sites
- Pancreatic cancer exosomes initiate pre-metastatic niche formation in the liver
- Migrating cancer stem cells — an integrated concept of malignant tumour progression
- Multistep nature of metastatic inefficiency: dormancy of solitary cells after successful extravasation and limited survival of early micrometastases.
- CD133+ ovarian cancer stem-like cells promote non-stem cancer cell metastasis via CCL5 induced epithelial-mesenchymal transition
- The pathogenesis of cancer metastasis: the 'seed and soil' hypothesis revisited
- Subclonal diversification of primary breast cancer revealed by multiregion sequencing
- Intravascular origin of metastasis from the proliferation of endothelium-attached tumor cells: a new model for metastasis
- Induction of tumor lymphangiogenesis by VEGF-C promotes breast cancer metastasis
- Stemness of the hybrid Epithelial/Mesenchymal State in Breast Cancer and Its Association with Poor Survival
- RNA-Seq of Single Prostate CTCs Implicates Noncanonical Wnt Signaling in Antiandrogen Resistance
- Distinct EMT programs control normal mammary stem cells and tumour-initiating cells
- Single-cell analysis reveals a stem-cell program in human metastatic breast cancer cells
- Foxa2 and Cdx2 cooperate with Nkx2-1 to inhibit lung adenocarcinoma metastasis
- Mutation selection and the natural history of cancer
- Platelets at the interface of thrombosis, inflammation, and cancer.
- Metastatic competence can emerge with selection of pre-existing oncogenic alleles without a need of new mutations
- Lysis of tumor cells by natural killer cells in mice is impeded by platelets.
- CCL2 recruits inflammatory monocytes to facilitate breast tumor metastasis
Cited by
- Impaired Localization of Claudin-11 in Endometriotic Epithelial Cells Compared to Endometrial Cells
- Towards control of cellular decision-making networks in the epithelial-to-mesenchymal transition
- Tumor-educated platelets.
- Upregulation of SNAI2 and SOX9 mRNA versus downregulation of eight other EMT/stemness related genes in basal cell carcinoma
- Ribosome biogenesis during cell cycle arrest fuels EMT in development and disease
- Epithelial-type systemic breast carcinoma cells with a restricted mesenchymal transition are a major source of metastasis
- Long noncoding RNA MYOSLID promotes invasion and metastasis by modulating the partial epithelial-mesenchymal transition program in head and neck squamous cell carcinoma
- TGF-β signaling pathway: Therapeutic targeting and potential for anti-cancer immunity.
- Cancer Cell Signaling: Methods and Protocols
- The Epithelial-to Mesenchymal Transition: Methods and Protocols
- EMT and MET: necessary or permissive for metastasis?
- Insights into the Link Between Obesity and Cancer
- Computational methods to dissect gene regulatory networks in cancer
- Long Non-coding RNAs and their Role in Metastasis.
- Quantifying spontaneous metastasis in a syngeneic mouse melanoma model using real time PCR
- Formin-Dependent Adhesions are Required for Invasion by Epithelial Tissues
- Alveolar Rhabdomyosarcoma Decellularization.
- EMT: Present and future in clinical oncology
- Emerging Topics on Disseminated Cancer Cell Dormancy and the Paradigm of Metastasis
- Epigenetic Regulation of the Epithelial to Mesenchymal Transition in Lung Cancer
Related papers
- [Mechanism of cancer metastasis and its inhibition--a point of view from clinical aspects].
- Identifying drivers of metastasis; towards a systematic approach
- Unveiling the Unpredicted and Uncontrolled Metastasis of Cancer Cells: A Minireview
- Hypotheses explaining cancer metastasis
- Recent advances in microfluidic models for cancer metastasis research
- Cancer metastasis, challenges, progress and the opportunities.
- The cell periphery and metastasis.
- In silico modeling of cancer cell dissemination and metastasis