Pore-forming activity and structural autoinhibition of the gasdermin family

Keywords

Pyroptosis, Cardiolipin, Autophagy, Chemistry, Cell biology

References

• Functional Conservation of Gsdma Cluster Genes Specifically Duplicated in the Mouse GenomeShigekazu Tanaka, Youichi Mizushina, Yoriko Kato — 2013
• The deafness gene DFNA5 induces programmed cell death through mitochondria and MAPK-related pathwaysRicardo Aldarondo — 2015
• Nonsyndromic hearing impairment is associated with a mutation in DFNA5Lut Van Laer, E. H. Huizing, Margriet Verstreken — 1998
• Cleavage of GSDMD by inflammatory caspases determines pyroptotic cell deathJianjin Shi, Yue Zhao, Kun Wang — 2015
• Caspase-11 cleaves gasdermin D for non-canonical inflammasome signallingNobuhiko Kayagaki, Irma B. Stowe, Bettina L. Lee — 2015
• Structure and assembly of pore-forming proteins.Ioan Iacovache, Mirko Bischofberger, F Gisou van der Goot — 2010
• Statistical potential for assessment and prediction of protein structuresMin‐Yi Shen, Andrej Šali — 2006
• Defolliculated (dfl): a dominant mouse mutation leading to poor sebaceous gland differentiation and total elimination of pelage follicles.Rebecca M. Porter, Declan P. Lunny, G.M. Henderson — 2002
• Pyroptotic cell death defends against intracellular pathogensIne Jørgensen, Edward A. Miao — 2015
• Activation of the pseudokinase MLKL unleashes the four-helix bundle domain to induce membrane localization and necroptotic cell deathJoanne M. Hildebrand, Maria C. Tanzer, Isabelle S. Lucet — 2014
• A Bayesian View on Cryo-EM Structure DeterminationSjors H. W. Scheres — 2012
• A new mutation Rim3 resembling Redenis mapped close to retinoic acid receptor alpha (Rara) gene on mouse Chromosome 11Hajime Sato, Tsuyoshi Koide, Hiroshi Masuya — 2009
• Mutations in the gene encoding pejvakin, a newly identified protein of the afferent auditory pathway, cause DFNB59 auditory neuropathySedigheh Delmaghani, Francisco Castillo, Vincent Michel — 2006
• The mechanism of pore assembly for a cholesterol-dependent cytolysin: formation of a large prepore complex precedes the insertion of the transmembrane beta-hairpins.Laura A. Shepard, Oleg Ya. Shatursky, Arthur E. Johnson — 2000
• Dali server: conservation mapping in 3DLiisa Holm, Pï¿ ⁄ ivi Rosenstrï¿ ⁄ m — 2010
• Pathogenic pore-forming proteins: function and host response.Mirko Bischofberger, Ioan Iacovache, F. Gisou van der Goot — 2012
• SPIDER and WEB: processing and visualization of images in 3D electron microscopy and related fields.Joachim Frank, Michael Radermacher, Pawel A. Penczek — 1996
• Ca2+-induced fusion of phospholipid vesicles monitored by mixing of aqueous contentsJan Wilschut, Demetrios Papahadjopoulos — 1979
• The NLRC4 inflammasome receptors for bacterial flagellin and type III secretion apparatusYue Zhao, Jieling Yang, Jianjin Shi — 2011
• Noncanonical Inflammasome Activation by Intracellular LPS Independent of TLR4Nobuhiko Kayagaki, Michael T. Wong, Irma B. Stowe — 2013

Cited by

• A bioluminescent caspase-1 activity assay rapidly monitors inflammasome activation in cells.John T. Queenan — 2017
• Pyroptosis by Caspase11/4-Gasdermin-D Pathway in Alcoholic HepatitisShoaib Usman, Matthew L. Dennis — 2018
• Structures of the gasdermin D C-terminal domains reveal mechanisms of autoinhibitionZhonghua Liu, Chuanping Wang, Joseph K. Rathkey — 2018
• Pyroptosis versus necroptosis: similarities, differences, and crosstalkC. Giraldi — 2018
• Cell death and immunity: Gasdermins: the hole picture emergesYvonne Bordon — 2016
• GSDMD membrane pore formation constitutes the mechanism of pyroptotic cell deathLorenzo Sborgi, Sebastian Rühl, Estefania Mulvihill — 2016
• Active caspase-1 induces plasma membrane pores that precede pyroptotic lysis and are blocked by lanthanidesHana M. Russo, Joseph K. Rathkey, Andrea Boyd-Tressler — 2016
• Formation of membrane pores by gasdermin-N causes pyroptosisXiaopeng Qi — 2016
• Lysosomes in programmed cell death pathways: from initiators to amplifiersNežka Kavčič, Katarina Pegan, Boris Turk — 2017
• P2X7 receptor-mediated TG2 externalization: a link to inflammatory arthritis?Daniel Aeschlimann, Vera Knäuper — 2016
• Pore formation by GSDMD is the effector mechanism of pyroptosisMoritz M. Gaidt, Veit Hornung — 2016
• Hemorrhagic shock primes for lung vascular endothelial cell pyroptosis: role in pulmonary inflammation following LPSJie Yang, Yanfeng Zhao, Peng Zhang — 2016
• Nuclear Pore Permeabilization Is a Convergent Signaling Event in Effector-Triggered ImmunityYangnan Gu, Sophia G. Zebell, Zizhen Liang — 2016
• Pyroptosis is driven by non-selective gasdermin-D pore and its morphology is different from MLKL channel-mediated necroptosisXin Chen, Wanting He, Lichen Hu — 2016
• Gasdermins pore cell membrane to pyroptosisHuanhuan Liang, Yingfang Liu — 2016
• The killer protein Gasdermin DJohn A. Wright, Clare Bryant — 2016
• Mechanism and regulation of NLRP3 inflammasome activationYuan He, Hideki Hara, Gabriel Núñez — 2016
• Deviant Behavior: Tick-Borne Pathogens and Inflammasome SignalingDana K. Shaw, Erin E. McClure, Xiaowei Wang — 2016
• Plant Pathology: A Life and Death Struggle in Rice Blast Disease.Jian‐Min Zhou — 2016
• Interrogating the relevance of mitochondrial apoptosis for vertebrate development and postnatal tissue homeostasisSelma Tuzlak, Thomas Kaufmann, Andreas Villunger — 2016

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