A rapidly inactivating Ca2+-dependent K+ current in pheochromocytoma cells (PC12) of the rat
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Summary
It is concluded that PC12 cells have a rapidly inactivating Ca2- -dependent K+ current, and a possible explanation for the transient nature of this current may be the presence of an effective intracellular Ca2+ buffering (uptake or extrusion) system.
- Type
- article
- Published
- 2004-01-01
- Cited by
- 3
- References
- 35
- OpenAlex
- https://openalex.org/W2324387369
- Semantic Scholar
- https://api.semanticscholar.org/CorpusID:25116991
Keywords
Cardiac transient outward potassium current, Biophysics, Divalent, Tetrodotoxin, Chemistry
References
- A transient potassium conductance regulates the excitability of cultured hippocampal and spinal neurons
- Calcium-dependent current generating the afterhyperpolarization of hippocampal neurons.
- Release of [3H]norepinephrine from a clonal line of pheochromocytoma cells (PC12) by nicotinic cholinergic stimulation
- Establishment of a noradrenergic clonal line of rat adrenal pheochromocytoma cells which respond to nerve growth factor.
- A fast transient outward current in the rat sympathetic neurone studied under voltage‐clamp conditions.
- Voltage dependent calcium currents in PC12 growth cones and cells during NGF-induced cell growth
- Two distinct Ca-dependent K currents in bullfrog sympathetic ganglion cells.
- Pharmacological and physiological properties of the after‐hyperpolarization current of bullfrog ganglion neurones.
- Nerve growth factor modulates the drug sensitivity of neurotransmitter release from PC-12 cells.
- Properties of two calcium‐activated hyperpolarizations in rat hippocampal neurones.
- Catecholamine secretion in a rat pheochromocytoma cell line: two pathways for calcium entry.
- Action potential repolarization may involve a transient, Ca2+ -sensitive outward current in a vertebrate neurone
- Release, storage and uptake of catecholamines by a clonal cell line of nerve growth factor (NGF) responsive pheo-chromocytoma cells.
- Calcium‐dependent potassium conductance in guinea‐pig olfactory cortex neurones in vitro.
- Improved patch-clamp techniques for high-resolution current recording from cells and cell-free membrane patches
- Transient calcium‐dependent potassium current in magnocellular neurosecretory cells of the rat supraoptic nucleus.
- Conduction and selectivity in potassium channels
- "Calciosome," a cytoplasmic organelle: the inositol 1,4,5-trisphosphate-sensitive Ca2+ store of nonmuscle cells?
- Calcium‐activated outward current in voltage‐clamped hippocampal neurones of the guinea‐pig.
- Intracellular Ca2+ activates a fast voltage-sensitive K+ current in vertebrate sympathetic neurones
Cited by
- Somatic sodium channels of frog olfactory receptor neurones are inactivated at rest
- Electrophysiological properties of neurones in cultures from postnatal rat dentate gyrus
- Cyclic AMP-dependent phosphorylation modifies the gating properties of L-type Ca2+ channels in bovine adrenal chromaffin cells
- Inhibition of Ion Channels by Hirsutine in Rat Pheochromocytoma Cells
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