Release, storage and uptake of catecholamines by a clonal cell line of nerve growth factor (NGF) responsive pheo-chromocytoma cells.

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Summary

Findings indicate that PC12 cells can release catecholamines by means of an exocytotic secretion mechanism, store most of their endogenous catechlamines in chromaffin granules and/or vesicles and have an uptake1-type transport system for norepinephrine.

Type
article
Published
1977-07-01
Cited by
397
References
40

Keywords

Nerve growth factor, Veratridine, Catecholamine, Chromaffin cell, Reserpine

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