Improved patch-clamp techniques for high-resolution current recording from cells and cell-free membrane patches

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Summary

The extracellular patch clamp method, which first allowed the detection of single channel currents in biological membranes, has been further refined to enable higher current resolution, direct membrane patch potential control, and physical isolation of membrane patches.

Type
article
Published
1981-07-30
Cited by
8,130
References
24

Keywords

Patch clamp, Current (fluid), Membrane, Resolution (logic), Current clamp

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