Classification of low quality cells from single-cell RNA-seq data

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Summary

This work presents a generic approach for processing scRNA-seq data and detecting low quality cells, using a curated set of over 20 biological and technical features, which improves classification accuracy by over 30 % compared to traditional methods.

Type
article
Published
2016-02-17
Cited by
621
References
55
Access
Open access

Keywords

Biology, Embryonic stem cell, Computational biology, RNA, RNA-Seq

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