Natural Products as Sources of New Drugs from 1981 to 2014.
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Summary
This contribution is a completely updated and expanded version of the four prior analogous reviews that were published in this journal in 1997, 2003, 2007, and 2012, and the time frame has been extended to cover the 34 years from January 1, 1981, to December 31, 2014, for all diseases worldwide, and from 1950 (earliest so far identified) to December 2014 for all approved antitumor drugs worldwide.
- Type
- review
- Published
- 2016-02-07
- Cited by
- 5,104
- References
- 123
- Access
- Open access
- OpenAlex
- https://openalex.org/W2256742438
- Semantic Scholar
- https://api.semanticscholar.org/CorpusID:5809604
Keywords
Natural product, Natural (archaeology), Product (mathematics), Computer science, Medicine
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Cited by
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- Enabling techniques in the search for new antibiotics: Combinatorial biosynthesis of sugar‐containing antibiotics
- Phytomedicine-Modulating oxidative stress and the tumor microenvironment for cancer therapy.
- The Pharmacological Potential of Non-ribosomal Peptides from Marine Sponge and Tunicates
- Physapubescin, a natural withanolide as a kidney-type glutaminase (KGA) inhibitor.
- Comparative genomics uncovers the prolific and distinctive metabolic potential of the cyanobacterial genus Moorea
- Labdane diterpenoids as potential anti‐inflammatory agents
- Palladium(II)/N-Heterocyclic Carbene-Catalyzed Direct C-H Acylation of Heteroarenes with N-Acylsaccharins.
- Synthesis of naphthazarin derivatives and identification of novel thioredoxin reductase inhibitor as potential anticancer agent.
- Strategies to diversify natural products for drug discovery
- Antimicrobial discovery inspired by ecological interactions.
- Natural cyclopeptide RA-V inhibits the NF-κB signaling pathway by targeting TAK1
- Syntheses of C-ring modified dehydroabietylamides and their cytotoxic activity.
- In vitro antidermatophytic activity and cytotoxicity of extracts derived from medicinal plants and marine algae.
- Aliphatic C—H Oxidations for Late-Stage Functionalization
- Antibacterial and antioxidant activities for natural and synthetic dual-active compounds.
- Comparative Proteomic Profiling of Tumor-Associated Proteins in Human Gastric Cancer Cells Treated with Pectolinarigenin
- Challenges and Opportunities for Natural Product Discovery, Production, and Engineering in Native Producers versus Heterologous Hosts
- TiO2 Photocatalysis for Transfer Hydrogenation
- BIOFACQUIM: A Mexican Compound Database of Natural Products
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