Discovery and development of natural compounds into medicinal products
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Summary
An analysis covering the 30-year period to December 2010 indicated that approximately 39% of all 1,068 small-molecule new chemical entities were either a natural compound, close semi-synthetic analogue or a synthetic analogue of the natural product pharmacophore.
- Type
- article
- Published
- 2013-01-01
- Cited by
- 5
- References
- 0
- OpenAlex
- https://openalex.org/W1972699609
- Semantic Scholar
- https://api.semanticscholar.org/CorpusID:58452337
Keywords
Drug discovery, Natural product, Pharmacophore, Natural (archaeology), Biochemical engineering
References
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Cited by
- Nature Bank and the Queensland Compound Library: unique international resources at the Eskitis Institute for Drug Discovery.
- Natural Products as Sources of New Drugs from 1981 to 2014.
- Analysis of Physicochemical Properties for Drugs of Natural Origin.
- Medicinal plants and bioactive natural compounds for cancer treatment: Important advances for drug discovery
- Metal-free quinolylation of the primary amino groups of amino acid derivatives and peptides with dihydrooxazolo[3,2-a]quinoliniums
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