Enabling techniques in the search for new antibiotics: Combinatorial biosynthesis of sugar‐containing antibiotics
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Summary
This review describes the modern combinatorial biosynthetic approaches for polyketide synthase‐derived complex and aromatic polyketides, non‐ribosomal peptide synthetase‐directed lipo‐/glycopeptides, aminoglycosides, nucleoside antibiotics, and alkaloids, along with their therapeutic potential.
- Type
- article
- Published
- 2017-06-15
- Cited by
- 13
- References
- 148
- OpenAlex
- https://openalex.org/W27793719
- Semantic Scholar
- https://api.semanticscholar.org/CorpusID:32455560
Keywords
Business, Advertising
References
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Cited by
- New approaches to antibiotic discovery
- Biosynthetic pathways of aminoglycosides and their engineering.
- Parallel pathways in the biosynthesis of aminoglycoside antibiotics
- Diversifying Natural Products with Promiscuous Glycosyltransferase Enzymes via a Sustainable Microbial Fermentation Approach
- Influence of Aryl-Substituted Xylose Derivatives on Fermentation of Antifungal Antibiotic Imbricin
- On the catalytic activity of a GT1 family glycosyltransferase from Streptomyces venezuelae ISP5230.
- New Sipanmycin Analogues Generated by Combinatorial Biosynthesis and Mutasynthesis Approaches Relying on the Substrate Flexibility of Key Enzymes in the Biosynthetic Pathway
- Flavonoids, terpenoids, and polyketide antibiotics: Role of glycosylation and biocatalytic tactics in engineering glycosylation.
- Rapid Synthesis of a Natural Product-Inspired Uridine Containing Library.
- Biocatalyzed Synthesis of Glycostructures with Anti-infective Activity
- Recent advances in the biosynthetic pathway and structural modification of gentamicin
- The amazing world of antibiotics.
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