Activation of NK cells and T cells by NKG2D, a receptor for stress-inducible MICA.
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Summary
An activating immunoreceptor-MHC ligand interaction that may promote antitumor NK and T cell responses is defined.
- Type
- letter
- Published
- 1999-07-30
- Cited by
- 3,221
- References
- 16
- OpenAlex
- https://openalex.org/W2170069789
- Semantic Scholar
- https://api.semanticscholar.org/CorpusID:19470591
Keywords
NKG2D, Cytotoxic T cell, Major histocompatibility complex, MHC class I, Natural killer cell
References
- Dependence of Peptide Binding by MHC Class I Molecules on Their Interaction with TAP
- Cloning the differences between two complex genomes
- Association of DAP12 with activating CD94/NKG2C NK cell receptors.
- An activating immunoreceptor complex formed by NKG2D and DAP10.
- Identifying differences in mRNA expression by representational difference analysis of cDNA.
- Superantigen-dependent, cell-mediated cytotoxicity inhibited by MHC class I receptors on T lymphocytes.
- Molecular characterization of human CD94: A type II membrane glycoprotein related to the C‐type lectin superfamily
- Recognition of stress-induced MHC molecules by intestinal epithelial gammadelta T cells.
- Cloning of immunoglobulin-superfamily members associated with HLA-C and HLA-B recognition by human natural killer cells.
- Selective rejection of H–2-deficient lymphoma variants suggests alternative immune defence strategy
- Natural killer cell receptors.
- NKG2A Complexed with CD94 Defines a Novel Inhibitory Natural Killer Cell Receptor
- Expression, purification, crystallization and crystallographic characterization of the human MHC class I related protein MICA.
- DNA sequence analysis of NKG2, a family of related cDNA clones encoding type II integral membrane proteins on human natural killer cells
- NK cell receptors.
- Major Histocompatibility Complex Class I Molecules Modulate Activation Threshold and Early Signaling of T Cell Antigen Receptor–γ/δ Stimulated by Nonpeptidic Ligands
- Brief Definitive Report Major Histocompatibility Complex Class I Molecules Modulate Activation Threshold and Early Signaling of T Cell Antigen Receptor–�/ � Stimulated by Nonpeptidic Ligands
Cited by
- Signal transduction in natural killer cells.
- Schädigung respiratorischer Epithelzellen nach allogener Stammzelltransplantation in einem Zellkulturmodell der Graft-versus-Host Reaktion
- Definition of a novel binding site on CD8 cells for a conserved region of the MHC class Ib molecule Qa‐1 that regulates IFN‐γ expression
- The MICA region determines the first modifier locus in familial Mediterranean fever.
- The biology of natural killer cells in cancer, infection, and pregnancy.
- Further polymorphism of the MICA gene.
- Biology of Natural Killer Cells in Cancer and Infection
- Development of a sample bank and clinical database for the retrospective analysis of unrelated bone marrow transplants : a pilot study of 138 transplants using RSCA for high resolution HLA matching
- Selective associations with signaling proteins determine stimulatory versus costimulatory activity of NKG2D
- Study of MICA alleles in 201 African Americans by multiplexed single nucleotide extension (MSNE) typing.
- Functional expression and release of ligands for the activating immunoreceptor NKG2D in leukemia.
- Additional factor in some HLA DR3/DQ2 haplotypes confers a fourfold increased genetic risk of celiac disease.
- Structure and function of natural-killer-cell receptors
- Molecular interactions: stiff or floppy (or somewhere in between?).
- Major histocompatibility complex class I chain-related gene A in Thai psoriasis patients: MICA association as a part of human leukocyte antigen-B-Cw haplotypes.
- Contribution of MHC class I chain-related A (MICA) gene polymorphism to genetic susceptibility for systemic lupus erythematosus.
- Survival versus neglect: redefining thymocyte subsets based on expression of NKG2D ligand(s) and MHC class I
- Mucosal T lymphocytes—peacekeepers and warriors
- A Typing System for the Major Histocompatibility Complex Class I Chain Related Genes A and B Using Polymerase Chain Reaction with Sequence-Specific Primers
- Interleukin‐15 mediates protection against experimental tuberculosis: A role for NKG2D‐dependent effector mechanisms of CD8+ T cells
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