Association of DAP12 with activating CD94/NKG2C NK cell receptors.
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Summary
The results provide a molecular basis for the assembly of NK cell receptors for MHC class I involved in cellular activation and inhibition.
- Type
- article
- Published
- 1998-06-01
- Cited by
- 608
- References
- 67
- Access
- Open access
- OpenAlex
- https://openalex.org/W2022609860
- Semantic Scholar
- https://api.semanticscholar.org/CorpusID:30399568
Keywords
Biology, Receptor, Neuroscience, Association (psychology), Cell
References
- Applications of retrovirus-mediated expression cloning.
- Role of potentially charged transmembrane residues in targeting proteins for retention and degradation within the endoplasmic reticulum.
- Human natural killer cell receptors involved in MHC class I recognition are disulfide-linked heterodimers of CD94 and NKG2 subunits.
- Human NKR-P1A. A disulfide-linked homodimer of the C-type lectin superfamily expressed by a subset of NK and T lymphocytes.
- Human killer cell activatory receptors for MHC class I molecules are included in a multimeric complex expressed by natural killer cells.
- Immunoreceptor DAP12 bearing a tyrosine-based activation motif is involved in activating NK cells
- Human and mouse killer-cell inhibitory receptors recruit PTP1C and PTP1D protein tyrosine phosphatases.
- A family of human lymphoid and myeloid Ig-like receptors, some of which bind to MHC class I molecules.
- Ly-49 multigene family expressed by IL-2-activated NK cells.
- Biology of Natural Killer Cells
- Clonotypic differences in signaling from CD94 (kp43) on NK cells lead to divergent cellular responses.
- The HLA-E gene encodes two differentially regulated transcripts and a cell surface protein.
- HLA-E surface expression depends on binding of TAP-dependent peptides derived from certain HLA class I signal sequences.
- Natural killer cell cytolytic activity is inhibited by NKG2-A and activated by NKG2-C.
- Biochemical and serologic evidence for the existence of functionally distinct forms of the CD94 NK cell receptor.
- Molecular cloning of NKB1. A natural killer cell receptor for HLA-B allotypes.
- CD94 and a novel associated protein (94AP) form a NK cell receptor involved in the recognition of HLA-A, HLA-B, and HLA-C allotypes.
- The human major histocompatibility complex class Ib molecule HLA‐E binds signal sequence‐derived peptides with primary anchor residues at positions 2 and 9
- The role of natural killer cells in host-parasite interactions.
- Direct binding of a soluble natural killer cell inhibitory receptor to a soluble human leukocyte antigen-Cw4 class I major histocompatibility complex molecule.
Cited by
- Interaction of the NK cell inhibitory receptor Ly49A with H-2Dd: identification of a site distinct from the TCR site.
- The NKG2 natural killer cell receptor family: comparative analysis of promoter sequences
- The biology of natural killer cells in cancer, infection, and pregnancy.
- Biology of Natural Killer Cells in Cancer and Infection
- Complex expression of natural killer receptor genes in single natural killer cells
- Immune-refractory cancers and their little helpers--an extended role for immunetolerogenic MHC molecules HLA-G and HLA-E?
- Development and Function of CD94-Deficient Natural Killer Cells
- Phenotypic and functional studies of NK cells in neonates and during early childhood
- Functional Anti‐CD94/NKG2A and Anti‐CD94/NKG2C Autoantibodies in Patients With Systemic Lupus Erythematosus
- NKG2C copy number variations in five distinct populations in mainland China and susceptibility to nasopharyngeal carcinoma (NPC).
- Intravenous Immunoglobulin Suppresses Abortion Relates to an Increase in the CD44bright NK Subset in Recurrent Pregnancy Loss Model Mice1
- Impacto de los inhibidores de Deacetilasas de Histonas (iHDAC) sobre la funcionalidad de células NK
- Heat shock proteins in immunity.
- Etude des mécanismes régulateurs des cellules NK : rôle de la molécule PD-1 et de la prostaglandine E2 (PGE2)
- Regulation of NK cell functions through interaction of the CD94/NKG2 receptors with the nonclassical class I molecule HLA-E.
- Biology of immunoreceptor tyrosine-based inhibition motif-bearing molecules.
- Engraftment of embryonic stem cell-derived hematopoietic progenitor cells is regulated by natural killer cells
- Cloning and Characterization of DAP10 homologue gene from Olive Flounder, Paralichthys olivaceus
- The enigma of activating isoforms of ITIM-bearing molecules.
- MIC genes: from genetics to biology.
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