Interleukin‐15 mediates protection against experimental tuberculosis: A role for NKG2D‐dependent effector mechanisms of CD8+ T cells
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Summary
It is concluded that in addition to regulating the expansion of CD8+ T’cells, IL‐15 is also necessary for inducing effector mechanisms in CD8- T cells that depend on NKG2D expression.
- Type
- article
- Published
- 2006-05-01
- Cited by
- 48
- References
- 58
- OpenAlex
- https://openalex.org/W16619285
- Semantic Scholar
- https://api.semanticscholar.org/CorpusID:43243586
Keywords
Estimator, Mathematics, Statistics, Econometrics
References
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- Cutting Edge: Toll-Like Receptor Signaling in Macrophages Induces Ligands for the NKG2D Receptor 1
- Overexpression of IL-15 In Vivo Enhances Protection Against Mycobacterium bovis Bacillus Calmette-Guérin Infection Via Augmentation of NK and T Cytotoxic 1 Responses1
- A protective role of interleukin-15 in a mouse model for systemic infection with herpes simplex virus.
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- CD8+ T Cells Participate in the Memory Immune Response to Mycobacterium tuberculosis
- Role of NKG2D signaling in the cytotoxicity of activated and expanded CD8+ T cells.
- Immune control of tuberculosis by IFN-gamma-inducible LRG-47.
- Roles of the NKG2D immunoreceptor and its ligands
- Potent and selective stimulation of memory-phenotype CD8+ T cells in vivo by IL-15.
- Interleukin 7 and T cell receptor signals regulate homeostasis of CD4 memory cells
- NKG2D recruits two distinct adapters to trigger NK cell activation and costimulation
- How can immunology contribute to the control of tuberculosis?
- An activating immunoreceptor complex formed by NKG2D and DAP10.
- IL-15 receptor maintains lymphoid homeostasis by supporting lymphocyte homing and proliferation.
- Interleukin-7 or Interleukin-15 Enhances Survival of Mycobacterium tuberculosis-Infected Mice
- Control of latent Mycobacterium tuberculosis infection is dependent on CD8 T cells
Cited by
- High IL-6 and low IL-15 levels mark the presence of TB infection: A preliminary study.
- The Immune Response to Acute HIV-1 Infection and the Effect of HAART and HLA Alleles on the Control of Viral Replication
- The role of pulmonary dendritic cells in regulating the antigen-specific CD8 T cell response following influenza virus infection
- Modulation des fonctions des lymphocytes T CD8 par l'Interleukine-4 et les cytokines de la famille γc
- NK Cells Enhance Dendritic Cell Response against Parasite Antigens via NKG2D Pathway1
- Autoantibody Profiles in Collagen Disease Patients with Interstitial Lung Disease (ILD): Antibodies to Major Histocompatibility Complex Class I-Related Chain A (MICA) as Markers of ILD
- Combination of host susceptibility and Mycobacterium tuberculosis virulence define gene expression profile in the host
- Containment of aerogenic Mycobacterium tuberculosis infection in mice does not require MyD88 adaptor function for TLR2, ‐4 and ‐9
- Cell-mediated immunity and the challenges for vaccine development.
- DAP10 contributes to CD8(+) T cell-mediated cytotoxic effector mechanisms during Mycobacterium tuberculosis infection.
- Influence of In Vitro IL-2 or IL-15 Alone or in Combination with Hsp-70-Derived 14-mer Peptide (TKD) on the Expression of NK Cell Activatory and Inhibitory Receptors
- The role of Interleukin-15 in inflammation and immune responses to infection: implications for its therapeutic use
- 4-1BB regulates NKG2D costimulation in human cord blood CD8+ T cells.
- Immunological profiling of tuberculosis-associated immune reconstitution inflammatory syndrome and non-immune reconstitution inflammatory syndrome death in HIV-infected adults with pulmonary tuberculosis starting antiretroviral therapy: a prospective observational cohort study
- NKG2D ligands in tumor immunity
- A Multi-valent Vaccinia Virus-based Tuberculosis Vaccine Molecularly Adjuvanted with Interleukin-15 Induces Robust Immune Responses in Mice
- Development of an IL-15-autocrine CD8 T-cell leukemia in IL-15-transgenic mice requires the cis expression of IL-15Rα.
- IL‐15 protects antigen‐specific CD8+ T cell contraction after Mycobacterium bovis bacillus Calmette‐Guérin infection
- Role of IL-15 and IL-21 in viral immunity: applications for vaccines and therapies
- NKG2D ligands as therapeutic targets.
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