Direct Reprogramming of Fibroblasts into Functional Cardiomyocytes by Defined Factors
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Summary
It is demonstrated that functional cardiomyocytes can be directly reprogrammed from differentiated somatic cells by defined factors, and might provide a source of cardiomyocytes for regenerative approaches.
- Type
- article
- Published
- 2010-08-06
- Cited by
- 2,450
- References
- 49
- Access
- Open access
- OpenAlex
- https://openalex.org/W2167202160
- Semantic Scholar
- https://api.semanticscholar.org/CorpusID:8599950
Keywords
Biology, Reprogramming, Cell biology, Genetics, Cell
References
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- Thy-1 expression by cardiac fibroblasts: lack of association with myofibroblast contractile markers.
Cited by
- Molecular and cellular basis of hematopoietic stem cells maintenance and differentiation
- Biology of the Mi-2/NuRD Complex in SLAC (Stemness, Longevity/Ageing, and Cancer)
- Development of Myocardial Constructs Using Modulus-Matched Acrylated Polypropylene Glycol Triol Substrate and Different Nonmyocyte Cell Populations
- Return to youth with Sox17.
- A case of cellular alchemy: lineage reprogramming and its potential in regenerative medicine.
- Human Amniotic Mesenchymal Stem Cell-Derived Induced Pluripotent Stem Cells May Generate a Universal Source of Cardiac Cells
- Structural immaturity of induced pluripotent stem cell-derived cardiomyocytes.
- Modeling human disease with pluripotent stem cells: from genome association to function.
- Advances in Culture and Manipulation of Human Pluripotent Stem Cells
- Reprogram or reboot: small molecule approaches for the production of induced pluripotent stem cells and direct cell reprogramming.
- De Novo Formation of Insulin-Producing “Neo-β Cell Islets” from Intestinal Crypts
- Strategies and Processes to Decellularize and Recellularize Hearts to Generate Functional Organs and Reduce the Risk of Thrombosis
- Cardiac Regeneration
- Modeling Neurological Disease by Rapid Conversion of Human Urine Cells into Functional Neurons
- Direct Reprogramming of Hepatic Myofibroblasts into Hepatocytes In Vivo Attenuates Liver Fibrosis.
- Targeting Mll1 H3K4 methyltransferase activity to guide cardiac lineage specific reprogramming of fibroblasts
- Possible Muscle Repair in the Human Cardiovascular System
- Cell Therapies in Cardiomyopathy: Current Status of Clinical Trials
- Systemic evaluation of cellular reprogramming processes exploiting a novel R-tool: eegc
- Regulation of Cell Cycle to Stimulate Adult Cardiomyocyte Proliferation and Cardiac Regeneration
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