Projection of an Immunological Self Shadow Within the Thymus by the Aire Protein

Keywords

Shadow (psychology), Projection (relational algebra), Biology, Immunology, Psychology

References

• T cell tolerance and autoimmunity.Kristine M. Garza, Vera S. F. Chan, Pamela S. Ohashi — 2000
• Medullary thymic epithelial cells induce tolerance to intracellular proteins.Mohamed Oukka, Michel Cohen‐Tannoudji, Yuka Tanaka — 1996
• Promiscuous gene expression in medullary thymic epithelial cells mirrors the peripheral selfJens Derbinski, Antje Schulte, Bruno Kyewski — 2001
• Shaping of the autoreactive T-cell repertoire by a splice variant of self protein expressed in thymic epithelial cellsLudger Klein, Matthias Klugmann, Klaus-Armin Nave — 2000
• Normal Thymic Architecture and Negative Selection Are Associated with Aire Expression, the Gene Defective in the Autoimmune-Polyendocrinopathy-Candidiasis-Ectodermal Dystrophy (APECED)1Saulius Žuklys, Gina Balc̆iūnaite, Anni Agarwal — 2000
• Thymic expression of autoantigens correlates with resistance to autoimmune disease.Charles E. Egwuagu, Puwat Charukamnoetkanok, Igal Gery — 1997
• Sampling of complementing self‐antigen pools by thymic stromal cells maximizes the scope of central T cell toleranceLudger Klein, Bernd Roettinger, Bruno Kyewski — 2001
• CD4 T cell tolerance to nuclear proteins induced by medullary thymic epithelium.Mohamed Oukka, Emma Colucci‐Guyon, Phương Lan Trần — 1996
• Mechanisms of immune tolerance induction through the thymic expression of a peripheral tissue-specific protein.Scott Antonia, Terrence L. Geiger, Judith Miller — 1995
• Peripheral-antigen-expressing cells in thymic medulla: factors in self-tolerance and autoimmunity.Douglas Hanahan — 1998
• Genetic susceptibility to post-thymectomy autoimmune diseases in miceAkinori Kojima, Richmond T. Prehn — 1981
• Self-antigen presentation by thymic stromal cells: a subtle division of labor.Ludger Klein, Bruno Kyewski — 2000
• Subcellular Location and Expression Pattern of Autoimmune Regulator (Aire), the Mouse Orthologue for Human Gene Defective in Autoimmune Polyendocrinopathy Candidiasis Ectodermal Dystrophy (APECED)Maria Halonen, Markku Pelto‐Huikko, Petra Eskelin — 2001
• T-cell tolerance toward a transgenic beta-cell antigen and transcription of endogenous pancreatic genes in thymus.Christine Jolicoeur, Douglas Hanahan, Karen Smith — 1994
• Insulin expression in human thymus is modulated by INS VNTR alleles at the IDDM2 locusPetros Vafiadis, Simon T. Bennett, John A. Todd — 1997
• AIRE mutations and human leukocyte antigen genotypes as determinants of the autoimmune polyendocrinopathy-candidiasis-ectodermal dystrophy phenotype.Maria Halonen, Petra Eskelin, Anne-Grethe Myhre — 2002
• CD4 T Cell Tolerance to Human C-reactive Protein, an Inducible Serum Protein, Is Mediated by Medullary Thymic EpitheliumLudger Klein, Thomas Klein, Ulrich Rüther — 1998
• RNA and protein expression of the murine autoimmune regulator gene (Aire) in normal, RelB‐deficient and in NOD mouseMaarit Heino, Pärt Peterson, Niko Sillanpää — 2000
• Deletion of high-avidity T cells by thymic epithelium.Matthias Hoffmann, William R. Heath, D Ruschmeyer — 1995
• The insulin gene is transcribed in the human thymus and transcription levels correlate with allelic variation at the INS VNTR-IDDM2 susceptibility locus for type 1 diabetesAlberto Pugliese, Markus Zeller, Alarico Fernandez — 1997

Cited by

• Review Article FoxP3: A Life beyond Regulatory T CellsYang Liu, Pan Zheng — 2009
• The role of TCR specificity in naturally arising CD25+ CD4+ regulatory T cell biology.Chyi‐Song Hsieh, Alexander Y. Rudensky — 2005
• The role of idiotype-specific immunity in antigen receptor diversityDavid G. Millar — 2010
• AIRE‐1 (Autoimmune Regulator Type 1) as a Regulator of the Thymic Induction of Negative SelectionGuillermo Muñoz‐Matutano, Fernando Sapiña — 2003
• Chronic mucocutaneous candidiasis and primary hypothyroidism in two families顕二 矢崎 — 2004
• Novel small GTPase subfamily capable of associating with tubulin is required for chromosome segregationFrancisco de Borja Medina — 2004
• Antibody repertoire development in fetal and neonatal piglets. XI. The thymic B‐cell repertoire develops independently from that in blood and mesenteric lymph nodes順子 有川, 直子 石黒, 眞 川島 — 2005
• Dependence of Self-Tolerance on TRAF6-Directed Development of Thymic Stroma卢善好, 吴开杰, 牛金海 — 2005
• Autoimmune polyendocrinopathy syndrome type 1 (APS1) and AIRE gene: new views on molecular basis of autoimmunity.Вегенер Юлия Сергеевна — 2005
• Aire-deficient mice develop hematopoetic irregularities and marginal zone B-cell lymphoma.Yun Jung Astrid Chan — 2006
• A vision of cell death: Fas ligand and immune privilege 10 years laterMaría Lucrecia Calderón Conejero — 2006
• Autoimmune polyendocrine syndrome type 1 in Norway: phenotypic variation, autoantibodies, and novel mutations in the autoimmune regulator gene.К А Петрова — 2007
• Limited Peripheral T Cell Anergy Predisposes to Retinal Autoimmunity1Rodrigo Inostroza Bidart — 2007
• Modest cortex and promiscuous medulla for thymic repertoire formation.Wacharachai Pusit — 2008
• Autoantigen-specific interactions with CD4+ thymocytes control mature medullary thymic epithelial cell cellularity.B.D. Duggins, Tommy D Goolsby, R.A. Benham — 2008
• The variable immunological self: Genetic variation and nongenetic noise in Aire-regulated transcriptionEmily S. Venanzi, Rachel Melamed, Diane Mathis — 2008
• Central tolerance: what have we learned from mice?Wendy C Robertson — 2008
• Overexpressing autoimmune regulator regulates the expression of toll-like receptors by interacting with their promoters in RAW264.7 cells.Wufei Zhu, Wei Yang, Zhifei He — 2011
• Effects of RANKL on the thymic medullaS. M. Khairnar, Meena More — 2011
• Targeting IL-1 in Sjögren's syndromeAldo Luis de Cunto — 2013

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