Modest cortex and promiscuous medulla for thymic repertoire formation.

Keywords

Devaluation, Financial crisis, Economics, Falling (accident), Economic policy

References

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• Cathepsin L Regulates CD4+ T Cell Selection Independently of Its Effect on Invariant ChainRafael Puyó Hernández — 2002
• Transcription of a broad range of self-antigens in human thymus suggests a role for central mechanisms in tolerance toward peripheral antigens.Mireia Sospedra, Xavier Ferrer-Francesch, Orlando Domı́nguez — 1998
• Noninvasive Intravital Imaging of Thymocyte Dynamics in Medaka1Jie Li, Norimasa Iwanami, Vu Quynh Hoa — 2007
• Shaping of the autoreactive T-cell repertoire by a splice variant of self protein expressed in thymic epithelial cellsLudger Klein, Matthias Klugmann, Klaus-Armin Nave — 2000
• Normal Thymic Architecture and Negative Selection Are Associated with Aire Expression, the Gene Defective in the Autoimmune-Polyendocrinopathy-Candidiasis-Ectodermal Dystrophy (APECED)1Saulius Žuklys, Gina Balc̆iūnaite, Anni Agarwal — 2000
• CD4/CD8 coreceptors in thymocyte development, selection, and lineage commitment: analysis of the CD4/CD8 lineage decision.Alfred Singer, Rémy Bosselut — 2004
• Mechanisms of immune tolerance induction through the thymic expression of a peripheral tissue-specific protein.Scott Antonia, Terrence L. Geiger, Judith Miller — 1995
• Aberrant Expression of Tissue‐Specific Proteins in the Thymus: A Hypothesis for the Development of Central ToleranceWerdelin, Cordes, Jensen — 1998
• Peripheral-antigen-expressing cells in thymic medulla: factors in self-tolerance and autoimmunity.Douglas Hanahan — 1998
• The development of proteasome inhibitors as anticancer drugs.Julian Adams — 2004
• How the T cell repertoire becomes peptide and MHC specific.Eric S. Huseby, Janice White, Frances Crawford — 2005
• Intrathymic expression of genes involved in organ specific autoimmune disease.Victoria L. Heath, Nel C. Moore, Sonia M. Parnell — 1998
• The proteasome: paradigm of a self-compartmentalizing protease.Wolfgang Baumeister, Jochen Walz, Frank Zühl — 1998
• Thymic microenvironments for T cell differentiation and selectionEna Ladi, Xinye Yin, Tatyana Chtanova — 2006
• The repertoire of T cells shaped by a single MHC/peptide ligand.Leszek Ignatowicz, John W. Kappler, Philippa Marrack — 1996
• Regulation of CD8+ T Cell Development by Thymus-Specific ProteasomesShigeo Murata, Katsuhiro Sasaki, Toshihiko Kishimoto — 2007
• CD4 T Cell Tolerance to Human C-reactive Protein, an Inducible Serum Protein, Is Mediated by Medullary Thymic EpitheliumLudger Klein, Thomas Klein, Ulrich Rüther — 1998
• Launching the T-cell-lineage developmental programmeEllen V. Rothenberg, Jonathan E. Moore, Mary A. Yui — 2008
• Promiscuous gene expression patterns in single medullary thymic epithelial cells argue for a stochastic mechanismJens Derbinski, Sheena Pinto, Stefanie Rösch — 2008

Cited by

• Development and function of thymocyte-selected CD4 T cellsYu Qiao — 2010
• Dissecting the thymic microenvironment - the impact of defective T cell development in the maintenance of the cortical thymic epitheliumP. Rodrigues — 2012
• Patients with thymomas have an increased risk of developing additional malignancies: lack of immunological surveillance?Felice Granato, Maria Raffaella Ambrosio, Donatella Spina — 2012
• Composition of the HLA‐DR‐associated human thymus peptidomeJavier Collado, Iñaki Álvarez, Marion Ciudad — 2013
• Thymic microenvironments for T-cell repertoire formation.Takeshi Nitta, Shigeo Murata, Tomoo Ueno — 2008
• Rare event simulation for probabilistic models of T-cell activationFlorian Lipsmeier — 2010
• Phenotypic and functional analysis of the mesenchymal stromal cell compartment in the thymusKatarzyna Sitnik — 2013
• Rapid Reconstitution of Antibody Responses Following Transplantation of Purified Allogeneic Hematopoietic Stem CellsJessica A. Linderman, Judith A. Shizuru — 2011
• The Importance of the Nurse Cells and Regulatory Cells in the Control of T Lymphocyte ResponsesMaría Guadalupe Reyes García, Fernando García Tamayó — 2012
• Activity-Based Profiling Reveals Reactivity of the Murine Thymoproteasome-Specific Subunit β5tBogdan I. Florea, Martijn Verdoes, Nan Li — 2010
• Repertoire Development and the Control of Cytotoxic/Effector Function in Human γ δ T CellsElizabeth Urban, Andrei I. Chapoval, C. David Pauza — 2010
• Thymoproteasome shapes immunocompetent repertoire of CD8+ T cells.Takeshi Nitta, Shigeo Murata, Katsuhiro Sasaki — 2010
• Molecular mechanisms of proteasome assemblyShigeo Murata, Hideki Yashiroda, Keiji Tanaka — 2009
• Targeting the Ubiquitin-proteasome system for the Treatment of Multiple Myeloma and Other Human DiseasesKlaus Podar, Kenneth C. Anderson — 2010
• β5t-containing thymoproteasome: specific expression in thymic cortical epithelial cells and role in positive selection of CD8+ T cells.Yousuke Takahama, Kensuke Takada, Shigeo Murata — 2012
• Thymoproteasome: Role in Thymic Selection and Clinical Significance as a Diagnostic Marker for Thymic Epithelial TumorsUtano Tomaru, Masanori Kasahara — 2013
• Sugar amino acid based peptide epoxyketones as potential proteasome inhibitors.Martijn Risseeuw, Bogdan I. Florea, Gijsbert A. van der Marel — 2010
• Role of thymic cortex-specific self-peptides in positive selection of T cells.Yousuke Takahama, Takeshi Nitta, Adiratna Mat Ripen — 2010
• On the issue of peptide recognition in T cell development.Travis J. Crites, Rajat Varma — 2010
• Low-affinity peptides and T-cell selection.Andreas Ziegler, Claudia Müller, Rainer A. Böckmann — 2009

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