Pancreatic cancer genomes reveal aberrations in axon guidance pathway genes

Keywords

Biology, KRAS, Exome sequencing, Genetics, Pancreatic cancer

References

• The deubiquitinase USP9X suppresses pancreatic ductal adenocarcinomaAustralian Pancreatic Cancer Genome Initiative, Pedro A. Pérez–Mancera, Alistair G. Rust — 2012
• Systematic investigation of genetic vulnerabilities across cancer cell lines reveals lineage-specific dependencies in ovarian cancerHiu Wing Cheung, Glenn S. Cowley, Barbara A. Weir — 2011
• Cancer research: past, present and futureYa Cao, Ronald A. DePinho, Matthias Ernst — 2011
• Somatic mutations in the chromatin remodeling gene ARID1A occur in several tumor typesSiân Jones, Meng Li, D. Williams Parsons — 2011
• Exome sequencing of liver fluke–associated cholangiocarcinomaChoon Kiat Ong, Chutima Subimerb, Chawalit Pairojkul — 2012
• Novel roles for Slits and netrins: axon guidance cues as anticancer targets?Patrick Mehlen, Céline Delloye‐Bourgeois, Alain Chédotal — 2011
• Somatic variation and cancer: therapies lost in the mixAndrew V. Biankin, Thomas J. Hudson — 2011
• In Vitro and in Vivo Characterization of a Novel Semaphorin 3A Inhibitor, SM-216289 or Xanthofulvin*Kaoru Kikuchi, Akiyoshi Kishino, Osamu Konishi — 2003
• The molecular and cellular heterogeneity of pancreatic ductal adenocarcinomaNardin Samuel, Thomas J. Hudson — 2012
• A Prospective Comparison of the Prognostic Value of Tumor- and Patient-Related Factors in Patients Undergoing Potentially Curative Surgery for Pancreatic Ductal AdenocarcinomaNigel B. Jamieson, S Denley, Jennifer Logue — 2011
• The patterns and dynamics of genomic instability in metastatic pancreatic cancerPeter J. Campbell, Shinichi Yachida, Laura Mudie — 2010
• Series Introduction: Invasive growth: from development to metastasisPaolo M. Comoglio, Livio Trusolino — 2002
• Genome profiling of pancreatic adenocarcinomaDavid Birnbaum, José Adélaı̈de, Émilie Mamessier — 2011
• Scatter-factor and semaphorin receptors: cell signalling for invasive growthLivio Trusolino, Paolo M. Comoglio — 2002
• Association of axon guidance factor Semaphorin 3A with poor outcome in pancreatic cancerMichael W. Müller, Nathalia A. Giese, Jakub M. Swiercz — 2007
• The brain within the tumor: new roles for axon guidance molecules in cancersAlain Chédotal, Géraldine Kerjan, Caroline Moreau‐Fauvarque — 2005
• Semaphorin signaling in cancer cells and in cells of the tumor microenvironment – two sides of a coinLorena Capparuccia, Luca Tamagnone — 2009
• The divergent Robo family protein rig-1/Robo3 is a negative regulator of slit responsiveness required for midline crossing by commissural axons.Christelle Sabatier, Andrew Plump, Le Ma — 2004
• The role of neuropilins in cancerLee M. Ellis — 2006
• Exome sequencing identifies frequent mutation of the SWI/SNF complex gene PBRM1 in renal carcinomaIgnacio Varela, Patrick Tarpey, Keiran Raine — 2011

Cited by

• Pancreatic Cancer Experimental and Clinical StudiesDavid Ljungman — 2013
• Understanding pancreatic cancer genomesQizhi Feng, Chunwu Yang, Xiuyun Lin — 2013
• Sympathetic innervation during development is necessary for pancreatic islet architecture and functional maturationAdria Steinberg, Kathleen Cushman, Robert J. Riordan — 2013
• Clinical and molecular characterization of HER2 amplified-pancreatic cancerPedro González Mira — 2013
• Deconvolving tumor purity and ploidy by integrating copy number alterations and loss of heterozygositySalvador Castaneda Vega, Laura Castillo Fuentes, Jonathan Gómez Hernández — 2014
• Cell signaling events differentiate ER-negative subtypes from ER-positive breast cancer英雄 内川, 晋一郎 横山, 修 濱崎 — 2015
• Frequency and distribution of Notch mutations in tumor cell linesAntônio Giacomini Ribeiro — 2015
• Clinical Sequencing Contributes to a BRCA-Associated Cancer Rediagnosis That Guides an Effective Therapeutic Course.Jocelyn Chapman, Saurabh Asthana, Lindsay Cade — 2015
• Phytochemical Properties and Anti-Proliferative Activity of Olea europaea L. Leaf Extracts against Pancreatic Cancer CellsH. Yamagata, Mitsuhiro Fujimoto — 2015
• Whole Exome Sequencing of Rapid Autopsy Tumors and Xenograft Models Reveals Possible Driver Mutations Underlying Tumor ProgressionЗахаров Александр Александрович — 2015
• Have lessons from past failures brought us closer to the success of immunotherapy in metastatic pancreatic cancer?J.C. Marco, S. Menéndez, M. Moreno — 2015
• Trial Watch: Targeting ATM–CHK2 and ATR–CHK1 pathways for anticancer therapy史朗 中村 — 2015
• Histone deacetylase class-I inhibition promotes epithelial gene expression in pancreatic cancer cells in a BRD4- and MYC-dependent mannerChandler Ahrens — 2017
• Susceptibility of ATM-deficient pancreatic cancer cells to radiationHideyuki Shimonishi, Hiroshi Suzuki — 2017
• Next generation sequencing of pancreatic ductal adenocarcinoma: right or wrong?Francis Antonietti, Mullis Stefan — 2017
• ATM-deficiency increases genomic instability and metastatic potential in a mouse model of pancreatic cancerYiannis Drosos, David Escobar, Ming-Yi Chiang — 2017
• ANO9/TMEM16J promotes tumourigenesis via EGFR and is a novel therapeutic target for pancreatic cancerNadine Marie Medlin — 2017
• Clinical Implications of NRAS Overexpression in Resectable Pancreatic Adenocarcinoma PatientsZanariah Ismail, Mohamad Sahari Nordin — 2017
• Molecular classification as prognostic factor and guide for treatment decision of pancreatic cancer.Jacques Dubosson, Margarita Mizraji — 2018
• Dietary cholesterol promotes steatohepatitis related hepatocellular carcinoma through dysregulated metabolism and calcium signalingLucina Jiménez — 2018

Related papers

• Long-term survivors of pancreatic adenocarcinoma show low rates of genetic alterations in KRAS, TP53 and SMAD4Michele Masetti, Giorgia Acquaviva, Michela Visani — 2017
• The GENCODE exome: sequencing the complete human exomeAlison J. Coffey, Felix Kokocinski, Maria S Calafato — 2011
• The current landscape of clinical exome and genome reanalysis in the U.S.Michelle Frees, Jennefer N. Carter, Matthew T. Wheeler — 2024
• Clinical Exome Performance for Reporting Secondary Genetic FindingsJason Y. Park, Peter Clark, Eric Londin — 2014
• Exome Sequencing in Mendelian DisordersJong‐Keuk Lee — 2010
• Diagnostic exome sequencing--are we there yet?Heather C. Mefford — 2012
• A comparative analysis of exome captureJennifer Parla, Ivan Iossifov, Ian Grabill — 2011
• Exome sequencing for neurological disordersJeffery M. Vance, Mustafa Tekin — 2017
• Abstract 1349: Improved human exome sequencing workflow with the most complete coverageManqing Hong, Bosun Min, Nicole Roseman — 2020
• [The application of exome sequencing in human disease].Shuquan Rao, Tingfu Du, Qi Xu — 2014