Somatic mutations in the chromatin remodeling gene ARID1A occur in several tumor types
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Summary
It is suggested that the aberrant chromatin remodeling consequent to ARID1A inactivation contributes to a variety of different types of neoplasms.
- Type
- article
- Published
- 2011-10-18
- Cited by
- 296
- References
- 27
- Access
- Open access
- OpenAlex
- https://openalex.org/W2002218976
- Semantic Scholar
- https://api.semanticscholar.org/CorpusID:13576618
Keywords
Biology, ARID1A, Chromatin remodeling, SMARCA4, Cancer research
References
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- Endometriosis-associated ovarian carcinomas.
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- Frequent mutation of histone modifying genes in non-Hodgkin lymphoma
- Distinct mammalian SWI/SNF chromatin remodeling complexes with opposing roles in cell‐cycle control
- Exploring the Genomes of Cancer Cells: Progress and Promise
- Frequent BRG1/SMARCA4–inactivating mutations in human lung cancer cell lines
- SWI/SNF nucleosome remodellers and cancer
- Loss of BAF250a (ARID1A) is frequent in high‐grade endometrial carcinomas
- ARID1A Mutations in Endometriosis-Associated Ovarian Carcinomas
- An Integrated Genomic Analysis of Human Glioblastoma Multiforme
- The genetic landscape of the childhood cancer medulloblastoma
- Understanding the Words of Chromatin Regulation
- Somatic Frameshift Mutations in the BAX Gene in Colon Cancers of the Microsatellite Mutator Phenotype
- Quantitative Selection Constants
- Systematic sequencing of renal carcinoma reveals inactivation of histone modifying genes
Cited by
- Aberrant promoter hypermethylation of PBRM1, BAP1, SETD2, KDM6A and other chromatin-modifying genes is absent or rare in clear cell RCC
- The chromatin remodelling component SMARCB1/INI1 influences the metastatic behavior of colorectal cancer through a gene signature mapping to chromosome 22
- ATP-Dependent Chromatin Remodeling Complexes as Novel Targets for Cancer Therapy
- Methylation of ras association domain protein 10 (RASSF10) promoter negative association with the survival of gastric cancer.
- Functional characterisation of driver events in ovarian clear cell carcinoma
- Clinical implications of genomic alterations in the tumour and circulation of pancreatic cancer patients
- Epigenetic Regulation of the Intestinal Epithelium
- ARID1A expression in gastric adenocarcinoma: clinicopathological significance and correlation with DNA mismatch repair status.
- Poor survival is associated with the methylated degree of zinc-finger protein 545 (ZNF545) DNA promoter in gastric cancer
- Exome sequencing reveals frequent inactivating mutations in ARID1A, ARID1B, ARID2 and ARID4A in microsatellite unstable colorectal cancer
- Genetic variants in the SWI/SNF complex and smoking collaborate to modify the risk of pancreatic cancer in a Chinese population
- Rhabdoid Tumors: An Initial Clue to the Role of Chromatin Remodeling in Cancer
- Detecting somatic mutations in genomic sequences by means of Kolmogorov–Arnold analysis
- Mutational landscape of mucinous ovarian carcinoma and its neoplastic precursors
- SWI/SNF Chromatin Remodeling Complexes and Cancer
- Functional analysis of in-frame indel ARID1A mutations reveals new regulatory mechanisms of its tumor suppressor functions.
- Genomic dynamics associated with malignant transformation in IDH1 mutated gliomas
- Endometriosis and ovarian cancer: links, risks, and challenges faced
- Gene mutations in gastric cancer: a review of recent next-generation sequencing studies
- Decreased ARID1A expression facilitates cell proliferation and inhibits 5-fluorouracil-induced apoptosis in colorectal carcinoma
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