The human T cell receptor in health and disease.
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Summary
It is likely that TCR-mediated disease susceptibility exists, and its basis at either a germline or somatic level will soon be clarified, according to current evidence in this area.
- Type
- review
- Published
- 1992-04-01
- Cited by
- 172
- References
- 68
- OpenAlex
- https://openalex.org/W2160899489
- Semantic Scholar
- https://api.semanticscholar.org/CorpusID:25268847
Keywords
Biology, Disease, Receptor, Genetics, Internal medicine
References
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- Evidence for the effects of a superantigen in rheumatoid arthritis.
- An endogenous retrovirus mediating deletion of αβ T cells?
- Flow cytometric and immunohistochemical characterization of the gamma/delta T-lymphocyte population in normal human lymphoid tissue and peripheral blood.
- T-cell receptor genes and insulin-dependent diabetes mellitus (IDDM): no evidence for linkage from affected sib pairs.
- Characterization and expression of the human alpha beta T cell receptor by using a framework monoclonal antibody.
- Properties of a panel of monoclonal antibodies which react with the human T cell antigen receptor on the leukemic line HPB-ALL and a subset of normal peripheral blood T lymphocytes.
- Staphylococcal exotoxin activation of T cells. Role of exotoxin-MHC class II binding affinity and class II isotype.
- Molecular genotypes of the human T cell receptor gamma-chain.
- New subgroups in the human T cell rearranging V gamma gene locus.
- The human T cell receptor beta-chain gene complex contains at least 57 variable gene segments. Identification of six V beta genes in four new gene families.
- Selective stimulation of human T cells with streptococcal erythrogenic toxins A and B.
- Rearrangement of two distinct T-cell γ-chain variable-region genes in human DNA
- Structure of T cell antigen receptor beta chain in synovial fluid cells from patients with rheumatoid arthritis.
- A superantigen encoded in the open reading frame of the 3′ long terminal repeat of mouse mammary tumour virus
- T-cell receptor alpha chain V region polymorphism linked to primary autoimmune hypothyroidism but not Graves' disease.
- A procedure for in vitro amplification of DNA segments that lie outside the boundaries of known sequences.
- Characterization of a third form of the human T cell receptor gamma/delta
- The human T cell antigen receptor is encoded by variable, diversity, and joining gene segments that rearrange to generate a complete V gene.
- Restricted use of T cell receptor V genes in murine autoimmune encephalomyelitis raises possibilities for antibody therapy.
Cited by
- T-cell repertoire diversity and clonal expansions in normal and clinical samples.
- Different distribution of T cell receptor beta-chain haplotypes in mixed connective tissue disease and systemic lupus erythematosus.
- Influence of non-inherited maternal HLA on disease development
- Immunization of the Neonate
- The HLA system. Second of two parts.
- Murine animal models to study the central role of T cells in immediate-type hypersensitivity responses.
- Mécanisme d'action et fonction d'une sous-population de cellules dendritiques cytotoxiques chez le rat
- System-wide approaches to uncover Th2 cell lineage commitment
- A study of artificial immune systems applied to anomaly detection
- The Human T-Cell Receptor Repertoire and Transplantation
- Analysis of CD45 variants effecting alternative splicing.
- Unveiling the biological role of serglycin proteoglycans
- Factores inmunitarios protectivos del huésped contra la infección por el VIH-1 y la progresión a SIDA: quimiocinas y sus receptores.
- Development of regulatory T cells in the human thymus
- Ex Vivo Characterization of Allo-MHC-Restricted T Cells Specific for a Single MHC-Peptide Complex1
- Studies of different clinical manifestations of Sarcoidosis and the role of genetic factors
- Pulmonary immune cells in health and disease: lymphocytes.
- Analysis of T cell receptor beta chain expression by isoelectric focusing following gene amplification and in vitro translation.
- Diversity of TCRAV and TCRBV sequences used by human T-cell clones specific for a minimal epitope of Bet v 1, the major birch pollen allergen
- The role of the B cells in the adoptive transfer of collagen‐induced arthritis from DBA/1 (H‐2q) to SCID (H−2d) mice
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