PSORT-B: improving protein subcellular localization prediction for Gram-negative bacteria
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Summary
PSORT-B, an updated version of PSORT for Gram-negative bacteria, is presented, designed to favor high precision over high recall (sensitivity), and attained an overall precision of 97% and recall of 75% in 5-fold cross-validation tests, using a dataset the authors developed of 1443 proteins of experimentally known localization.
- Type
- article
- Published
- 2003-07-01
- Cited by
- 444
- References
- 21
- Access
- Open access
- OpenAlex
- https://openalex.org/W2160072419
- Semantic Scholar
- https://api.semanticscholar.org/CorpusID:155451
Keywords
Biology, Computational biology, Subcellular localization, Source code, Probabilistic logic
References
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- The SWISS-PROT protein sequence database and its supplement TrEMBL in 2000
- PSORT: a program for detecting sorting signals in proteins and predicting their subcellular localization.
- Using neural networks for prediction of the subcellular location of proteins.
- The SWISS-PROT protein sequence data bank and its supplement TrEMBL
- Wanted: subcellular localization of proteins based on sequence.
- Extensive feature detection of N-terminal protein sorting signals
- Membrane protein biogenesis: the exception explains the rules.
- The PROSITE database, its status in 2002
- Predicting Protein Subcellular Localisation From Amino Acid Sequence Information
- Predicting subcellular localization of proteins based on their N-terminal amino acid sequence.
- A comparison of signal sequence prediction methods using a test set of signal peptides
- Principles governing amino acid composition of integral membrane proteins: application to topology prediction.
- Support vector machine approach for protein subcellular localization prediction
- Sequence conserved for subcellular localization
- Identification of prokaryotic and eukaryotic signal peptides and prediction of their cleavage sites.
- The PROSITE database, its status in 1999
Cited by
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- Genes for two multicopper proteins required for Fe(III) oxide reduction in Geobacter sulfurreducens have different expression patterns both in the subsurface and on energy-harvesting electrodes.
- FGsub: Fusarium graminearum protein subcellular localizations predicted from primary structures
- Computer aided selection of candidate vaccine antigens
- Proteins involved in electron transfer to Fe(III) and Mn(IV) oxides by Geobacter sulfurreducens and Geobacter uraniireducens.
- Computational Approaches To Anti-Toxin Therapies And Biomarker Identification
- Genómica funcional de Bordetella pertussis , implicancias sobre una enfermedad considerada reemergente
- Les Patatines de Pseudomonas Aeruginosa : secrétées ou non secrétées ? Telle est la question ...
- Protein Targeting Protocols
- Protein subcellular localization prediction using artificial intelligence technology.
- Prokaryotic protein subcellular localization prediction and genome-scale comparative analysis
- Decision making based on association rules
- SpeB–Spi: a novel protease–inhibitor pair from Streptococcus pyogenes
- Protein subcellular localization prediction for Gram-negative bacteria using amino acid subalphabets and a combination of multiple support vector machines
- Genome-scale prediction of protein subcellular location in bacteria, with focus on extracellular and surface-associated proteins.
- Characterisation of bacteriophages that infect Acaryochloris
- Expression profiling of hypothetical genes in Desulfovibrio vulgaris leads to improved functional annotation
- Clonagem e expressão gênica de antígenos candidatos vacinais contra leptospirose.
- Predicting protein subcellular locations using hierarchical ensemble of Bayesian classifiers based on Markov chains
- Genomic content of uncultured Bacteroidetes from contrasting oceanic provinces in the North Atlantic Ocean.
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