PSORT-B: improving protein subcellular localization prediction for Gram-negative bacteria

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Summary

PSORT-B, an updated version of PSORT for Gram-negative bacteria, is presented, designed to favor high precision over high recall (sensitivity), and attained an overall precision of 97% and recall of 75% in 5-fold cross-validation tests, using a dataset the authors developed of 1443 proteins of experimentally known localization.

Type
article
Published
2003-07-01
Cited by
444
References
21
Access
Open access

Keywords

Biology, Computational biology, Subcellular localization, Source code, Probabilistic logic

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