A comparison of signal sequence prediction methods using a test set of signal peptides
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Summary
Five existing prediction programs for signal sequences and their cleavage sites are compared on the basis of this test set and b2-HMM and SignalP V2.0.0 is described.
- Type
- article
- Published
- 2000-08-01
- Cited by
- 140
- References
- 7
- Access
- Open access
- OpenAlex
- https://openalex.org/W2153671224
- Semantic Scholar
- https://api.semanticscholar.org/CorpusID:21506098
Keywords
Signal peptide, SIGNAL (programming language), Set (abstract data type), Sequence (biology), Test set
References
- On the predictive recognition of signal peptide sequences.
- The SWISS-PROT protein sequence database and its supplement TrEMBL in 2000
- The SWISS-PROT protein sequence data bank and its supplement TrEMBL
- Machine learning approaches for the prediction of signal peptides and other protein sorting signals.
- A new method for predicting signal sequence cleavage sites.
- Prediction of Signal Peptides and Signal Anchors by a Hidden Markov Model
- SHORT COMMUNICATION Identification of prokaryotic and eukaryotic signal peptides and prediction of their cleavage sites
Cited by
- Human secretory signal peptide description by hidden Markov model and generation of a strong artificial signal peptide for secreted protein expression.
- Identification of essential amino acids in Humanin, a neuroprotective factor against Alzheimer's disease-relevant insults.
- Structure-Related Statistical Singularities along Protein Sequences: A Correlation Study
- Evaluation of text-mining systems for biology: overview of the Second BioCreative community challenge
- Fusion of Conditional Random Field and SignalP for Protein Cleavage Site Prediction
- MemO: A Consensus Approach to the Annotation of a Protein's Membrane Organization
- Comparative genomics for studying the proteomes of mucosal microorganisms
- Novel phospholipases A of Pseudomonas aeruginosa: biochemical characterisation and cellular localisation
- Evaluating Transmembrane Topology Prediction Methods for the Effect of Signal Peptide in Topology Prediction
- Evaluating eukaryotic secreted protein prediction
- Genome-scale prediction of protein subcellular location in bacteria, with focus on extracellular and surface-associated proteins.
- CHARACTERISATION, RECOMBINANT EXPRESSION AND IMMUNOGENICITY OF BHLP29.7, AN OUTER MEMBRANE LIPOPROTEIN OF BRACHYSPIRA HYODYSENTERIAE
- Graphical representation and mathematical characterization of protein sequences and applications to viral proteins
- SPdb – a signal peptide database
- Methods for Detecting the Signal Peptide in Transmembrane and Globular Proteins
- Mining the secretome of root-knot nematodes for cell wall modifying proteins
- Evaluating signal peptide prediction methods for Gram-positive bacteria
- Immuno‐informatics: Mining genomes for vaccine components
- Comprehensive proteome analysis of Actinoplanes sp. SE50/110 highlighting the location of proteins encoded by the acarbose and the pyochelin biosynthesis gene cluster.
- Automatic prediction of protein function
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