DNA Methylation and Its Basic Function
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Summary
The investigation into DNA methylation continues to show a rich and complex picture about epigenetic gene regulation in the central nervous system and provides possible therapeutic targets for the treatment of neuropsychiatric disorders.
- Type
- review
- Published
- 2013-01-01
- Cited by
- 4,110
- References
- 219
- Access
- Open access
- OpenAlex
- https://openalex.org/W2152656267
- Semantic Scholar
- https://api.semanticscholar.org/CorpusID:9793643
Keywords
DNA methylation, Epigenetics of physical exercise, Epigenetics, Biology, DNA demethylation
References
- Dissection of the methyl-CpG binding domain from the chromosomal protein MeCP2.
- Bidirectional action of the Igf2r imprint control element on upstream and downstream imprinted genes.
- A microRNA DNA methylation signature for human cancer metastasis
- Kaiso contributes to DNA methylation-dependent silencing of tumor suppressor genes in colon cancer cell lines.
- Methylated DNA and MeCP2 recruit histone deacetylase to repress transcription
- Deficiency of methyl-CpG binding protein-2 in CNS neurons results in a Rett-like phenotype in mice
- Loss of genomic methylation causes p53-dependent apoptosis and epigenetic deregulation
- Studies on the chemical nature of the substance inducing transformation of pneumococcal types. Inductions of transformation by a desoxyribonucleic acid fraction isolated from pneumococcus type III
- Inhibition of DNA methyltransferase and induction of Friend erythroleukemia cell differentiation by 5-azacytidine and 5-aza-2'-deoxycytidine.
- Transcription of IAP endogenous retroviruses is constrained by cytosine methylation
- DNA methyltransferase Dnmt1 associates with histone deacetylase activity
- The quantitative separation of purines, pyrimidines, and nucleosides by paper chromatography.
- Rett syndrome is caused by mutations in X-linked MECP2, encoding methyl-CpG-binding protein 2
- DNA hypomethylation leads to elevated mutation rates
- Imprinted expression of the Igf2r gene depends on an intronic CpG island
- MBD2 is a transcriptional repressor belonging to the MeCP1 histone deacetylase complex
- The thymine glycosylase MBD4 can bind to the product of deamination at methylated CpG sites
- Dnmt3L and the Establishment of Maternal Genomic Imprints
- Transcriptional repression by the methyl-CpG-binding protein MeCP2 involves a histone deacetylase complex
- Methyl-CpG-binding Protein, MeCP2, Is a Target Molecule for Maintenance DNA Methyltransferase, Dnmt1*
Cited by
- An epigenetic framework for neurodevelopmental disorders: from pathogenesis to potential therapy.
- HPA Axis Gene Expression and DNA Methylation Profiles in Rats Exposed to Early Life Stress, Adult Voluntary Ethanol Drinking and Single Housing
- Differential responsiveness of Holstein and Angus dermal fibroblasts to LPS challenge occurs without major differences in the methylome
- Childhood Adversity and Epigenetic Regulation of Glucocorticoid Signaling Genes: Associations in Children and Adults
- Recent advances in the neurobiology and neuropharmacology of Alzheimer's disease.
- Author Correction: Downregulation of PARP1 transcription by promoter-associated E2F4-RBL2-HDAC1-BRM complex contributes to repression of pluripotency stem cell factors in human monocytes
- Maternal exercise training attenuates endotoxin-induced sepsis in mice offspring
- DNA Methylation in Animal Models of Psychosis
- Tet2-mediated epigenetic drive for astrocyte differentiation from embryonic neural stem cells
- Understanding the microbial fibre degrading communities & processes in the equine gut
- The ATP2C2 Gene as Transcribed from a Novel Transcriptional Start Site in Pancreatic Acinar Cells
- Effetto dell’etanolo sullo stato di metilazione del gene che codifica per la neurotrofina “Brain-Derived Neurotrophic Factor”
- Expression of mouse Dab2ip transcript variants and gene methylation during brain development
- Proximate And Evolutionary Insights Into The Epigenetics Of Posttraumatic Stress Disorder
- Nucleolar epigenomics by dynamic molecular combing and nucleolar matrix analysis
- Determining Epigenetic Targets: A Beginner's Guide to Identifying Genome Functionality Through Database Analysis.
- Reversibility and heritability of liver fibrosis: Implications for research and therapy.
- The role of age-related DNA methylation in the development of age-related disease
- Developing a microRNA body fluid identification test for use in forensic casework
- With Gottlieb beyond Gottlieb: The Role of Epigenetics in Psychobiological Development
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