A stepwise huisgen cycloaddition process: copper(I)-catalyzed regioselective "ligation" of azides and terminal alkynes.
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- Type
- article
- Published
- 2002-07-15
- Cited by
- 9,320
- References
- 30
- OpenAlex
- https://openalex.org/W2145662716
- Semantic Scholar
- https://api.semanticscholar.org/CorpusID:19668001
Keywords
Regioselectivity, Cycloaddition, Terminal (telecommunication), Copper, Chemistry
References
- Modern Catalytic Methods for Organic Synthesis with Diazo Compounds: From Cyclopropanes to Ylides
- Peptidotriazoles on solid phase: [1,2,3]-triazoles by regiospecific copper(i)-catalyzed 1,3-dipolar cycloadditions of terminal alkynes to azides.
- Comprehensive Organometallic Chemistry. The Synthesis, Reactions, and Structures of Organometallic Compounds
- Asymmetric 1,3-Dipolar Cycloaddition Reactions.
- Molecular shuttles by the protecting group approach
- Cell surface engineering by a modified Staudinger reaction.
- Reactivity of Copper(I) Complexes Towards Dioxygen
- Reactions of Alkyl Azides and Ketones as Mediated by Lewis Acids: Schmidt and Mannich Reactions Using Azide Precursors
- Efficient recognition-induced acceleration of a [3+2] dipolar cycloaddition reaction
- 1.3-Dipolare Cycloadditionen, XXXII. Kinetik der Additionen organischer Azide an CC-Mehrfachbindungen
- 1,3-DIPOLAR CYCLOADDITION OF PHENYL AZIDE TO NORBORNENE IN AQUEOUS-SOLUTIONS
- Click Chemistry: Diverse Chemical Function from a Few Good Reactions.
- Complexities of ascorbate as a reducing agent
- Selectivity in an encapsulated cycloaddition reaction.
- Comprehensive Heterocyclic Chemistry IV
- Ab initio and Monte Carlo study of solvent eÜects on a 1,3–dipolar cycloaddition
- Reactivity of aryl and heteroaryl azides with vinylsilane and alkynylsilane. Formation of C-silylated 1,2,3-triazolines and 1,2,3-triazoles
- Recognition-mediated regiocontrol of a dipolar cycloaddition reaction
- Incorporation of azides into recombinant proteins for chemoselective modification by the Staudinger ligation
- Preparation and pyrolysis of 1-(pyrazol-5-yl)-1,2,3-triazoles andrelated compounds1
Cited by
- Recent advances toward the development of inhibitors to attenuate tumor metastasis via the interruption of lectin-ligand interactions.
- Addition reaction of azido-exTTFs to C60: synthesis of fullerotriazoline and azafulleroid electroactive dyads.
- Tandem azidination- and hydroazidination-Huisgen [3 + 2] cycloadditions of ynamides. Synthesis of chiral amide-substituted triazoles.
- A RSK kinase inhibitor reporting its selectivity in vivo.
- A liquid-crystalline bistable [2]rotaxane.
- Alkyne-Azide Click Chemistry Mediated Carbanucleosides Synthesis
- A one-pot synthesis of constitutionally unsymmetrical rotaxanes using sequential Cu(I)-catalyzed azide-alkyne cycloadditions.
- "Click chemistry" in zeolites: copper(I) zeolites as new heterogeneous and ligand-free catalysts for the Huisgen [3+2] cycloaddition.
- Cu(II)-hydrotalcite as an efficient heterogeneous catalyst for Huisgen [3+2] cycloaddition.
- Induction of a Melanoma‐Specific Antibody Response by a Monovalent, but not a Divalent, Synthetic GM2 Neoglycopeptide
- Adjustable receptor based on a [3]rotaxane whose two threaded rings are rigidly attached to two porphyrinic plates: synthesis and complexation studies.
- Novel prolinamide-camphor-containing organocatalysts for direct asymmetric Michael addition of unmodified aldehydes to nitroalkenes.
- Synthesis of fluorophosphonylated acyclic nucleotide analogues via copper(I)-catalyzed Huisgen 1-3 dipolar cycloaddition.
- Copper-catalyzed azide-alkyne cycloaddition: regioselective synthesis of 1,4,5-trisubstituted 1,2,3-triazoles.
- "Click" tetradentate ligands.
- Chemical modification of self-assembled silane based monolayers by surface reactions.
- New tetradentate N,N,N,N-chelating α-diimine ligands and their corresponding zinc and nickel complexes: synthesis, characterisation and testing as olefin polymerisation catalysts.
- Controlled release from cleavable polymerized liposomes upon redox and pH stimulation.
- Maintaining biological activity by using triazoles as disulfide bond mimetics.
- "Clickable", trifunctional magnetite nanoparticles and their chemoselective biofunctionalization.
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