Peptidotriazoles on solid phase: [1,2,3]-triazoles by regiospecific copper(i)-catalyzed 1,3-dipolar cycloadditions of terminal alkynes to azides.

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Summary

A novel regiospecific copper(I)-catalyzed 1,3-dipolar cycloaddition of terminal alkynes to azides on solid-phase is reported, and the X-ray structure of 2-azido-2-methylpropanoic acid has been solved, to yield structural information on the 1, 3-dipoles entering the reaction.

Type
article
Published
2002-04-02
Cited by
7,351
References
11

Keywords

Cycloaddition, Chemistry, 1,3-Dipolar cycloaddition, Combinatorial chemistry, Catalysis

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