Control of viremia in simian immunodeficiency virus infection by CD8+ lymphocytes.
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Summary
The results confirm the importance of cell-mediated immunity in controlling HIV-1 infection and support the exploration of vaccination approaches for preventing infection that will elicit these immune responses.
- Type
- article
- Published
- 1999-02-05
- Cited by
- 2,437
- References
- 15
- OpenAlex
- https://openalex.org/W2144882745
- Semantic Scholar
- https://api.semanticscholar.org/CorpusID:38716690
Keywords
Viremia, Simian immunodeficiency virus, Virology, Immune system, CD8
References
- Susceptibility Genes: Pointing a Way to Prevention?
- Immunopathogenic events in acute infection of rhesus monkeys with simian immunodeficiency virus of macaques
- Temporal association of cellular immune responses with the initial control of viremia in primary human immunodeficiency virus type 1 syndrome
- Variable course of primary simian immunodeficiency virus infection in lymph nodes: relation to disease progression
- CD8+ lymphocytes can control HIV infection in vitro by suppressing virus replication.
- Recombinant modified vaccinia virus Ankara-simian immunodeficiency virus gag pol elicits cytotoxic T lymphocytes in rhesus monkeys detected by a major histocompatibility complex class I/peptide tetramer.
- Reduction of HIV Concentration During Acute Infection: Independence from a Specific Immune Response
- A new reagent for the induction of T-cell depletion, anti-CD3-CRM9.
- Analysis of Gag-specific Cytotoxic T Lymphocytes in Simian Immunodeficiency Virus–infected Rhesus Monkeys by Cell Staining with a Tetrameric Major Histocompatibility Complex Class I–Peptide Complex
- The Unenlarged Lymph Nodes of HIV-1–infected, Asymptomatic Patients with High CD4 T Cell Counts Are Sites for Virus Replication and CD4 T Cell Proliferation. The Impact of Highly Active Antiretroviral Therapy
- Quantitation of HIV-1-specific cytotoxic T lymphocytes and plasma load of viral RNA.
- Administration of an Anti-CD8 Monoclonal Antibody Interferes with the Clearance of Chimeric Simian/Human Immunodeficiency Virus during Primary Infections of Rhesus Macaques
- Cytotoxic-T-cell responses, viral load, and disease progression in early human immunodeficiency virus type 1 infection.
Cited by
- An Antigenic Threshold for Maintaining Human Immunodeficiency Virus Type 1-specific Cytotoxic T Lymphocytes
- Adjuvant-Specific Serum Cytokine Profiles in the Context of a DNA Prime-Protein Boost HIV-1 Vaccine: A Dissertation
- Skin stem cells – a hairy issue.
- Evaluation of distinct blood lymphocyte populations in human immunodeficiency virus type 1-infected subjects in the absence or presence of effective therapy.
- MHC-restricted protection of cats against FIV infection by adoptive transfer of immune cells from FIV-vaccinated donors.
- High Levels of Viral Replication during Primary Simian Immunodeficiency Virus SIVagm Infection Are Rapidly and Strongly Controlled in African Green Monkeys
- Lessons learnt from studies of the immune characterization of naturally SIV infected sooty mangabeys.
- DNA prime/protein boost vaccine strategy in neonatal macaques against simian human immunodeficiency virus
- Importance of B-Cell Responses for Immunological Control of Variant Strains of Simian Immunodeficiency Virus
- Kaposi's Sarcoma-Associated Herpesvirus Cytotoxic T Lymphocytes Recognize and Target Darwinian Positively Selected Autologous K1 Epitopes
- Microanatomic Relationships Between CD8+ Cells and HIV-1-Producing Cells in Human Lymphoid Tissue in Vivo
- Cellular immune responses to helper-free HSV-1 amplicon particles encoding HIV-1 gp120 are enhanced by DNA priming.
- Enhanced cellular immune response against SIV Gag induced by immunization with DNA vaccines expressing assembly and release-defective SIV Gag proteins.
- Distinct clonal repertoire of brain CD8+ cells in simian immunodeficiency virus infection
- Qualitative T-Helper Responses to Multiple Viral Antigens Correlate with Vaccine-Induced Immunity to Simian/Human Immunodeficiency Virus Infection
- Enhanced cellular immunity and systemic control of SHIV infection by combined parenteral and mucosal administration of a DNA prime MVA boost vaccine regimen.
- Loss of HIV-1–specific CD8+ T Cell Proliferation after Acute HIV-1 Infection and Restoration by Vaccine-induced HIV-1–specific CD4+ T Cells
- Induction of Gag-specific T-cell responses by therapeutic immunization with a Gag-expressing Sendai virus vector in macaques chronically infected with simian-human immunodeficiency virus.
- Cytotoxic T lymphocytes in protection against equine infectious anemia virus
- The CD160+ CD8high cytotoxic T cell subset correlates with response to HAART in HIV-1+ patients.
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