Reduction of HIV Concentration During Acute Infection: Independence from a Specific Immune Response
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Summary
The reduction in virus concentration during acute infection may not reflect the ability of the HIV-specific immune response to control virus replication, as predicted by a model of the dynamics of early HIV infection.
- Type
- article
- Published
- 1996-01-26
- Cited by
- 331
- References
- 22
- OpenAlex
- https://openalex.org/W2013602955
- Semantic Scholar
- https://api.semanticscholar.org/CorpusID:36363689
Keywords
Virus, Immune system, Virology, Human immunodeficiency virus (HIV), Viral replication
References
- Viral dynamics in human immunodeficiency virus type 1 infection
- Evidence that T cell activation is required for HIV-1 entry in CD4+ lymphocytes.
- Quantitation of human immunodeficiency virus type 1 infection kinetics
- Temporal association of cellular immune responses with the initial control of viremia in primary human immunodeficiency virus type 1 syndrome
- Early viremia and immune responses in vertical human immunodeficiency virus type 1 infection.
- Population dynamics of HIV within an individual after treatment with zidovudine
- Shutting down HIV
- Rapid turnover of plasma virions and CD4 lymphocytes in HIV-1 infection
- Lifespan of human lymphocyte subsets defined by CD45 isoforms
- High levels of HIV-1 in plasma during all stages of infection determined by competitive PCR.
- Virus-specific CD8+ cytotoxic T-lymphocyte activity associated with control of viremia in primary human immunodeficiency virus type 1 infection
- Dynamics of HIV infection of CD4+ T cells.
- Characterization of human immunodeficiency virus type 1-specific cytotoxic T lymphocyte clones isolated during acute seroconversion: recognition of autologous virus sequences within a conserved immunodominant epitope
- A model for AIDS pathogenesis.
- A region of the third variable loop of HIV-1 gp120 is recognized by HLA-B7-restricted CTLs from two acute seroconversion patients.
- High titers of cytopathic virus in plasma of patients with symptomatic primary HIV-1 infection.
- Transient high levels of viremia in patients with primary human immunodeficiency virus type 1 infection.
- Cell Activation and Apoptosis in HIV Infection
- The New England journal of medicine
Cited by
- Development and application of non-integrating lentiviral vectors for gene therapy
- The role of early HIV infection in the spread of HIV through populations.
- Immune Restoration by Combination of a Cytostatic Drug (Hydroxyurea) and Anti-HIV Drugs (Didanosine and Indinavir)
- Incubation time of acute human immunodeficiency virus (HIV) infection and duration of acute HIV infection are independent prognostic factors of progression to AIDS.
- Limits on Replenishment of the Resting CD4+ T Cell Reservoir for HIV in Patients on HAART
- HIV Gag p24 specific responses secreting IFN-gamma and/or IL-2 in treatment-naïve individuals in acute infection early disease (AIED) are associated with low viral load.
- HIV Replication Is Not Controlled by CD8+ T Cells during the Acute Phase of the Infection in Humanized Mice
- A NEW MATHEMATICAL INDEX FOR THE OPTIMAL CONTROL OF DRUG DOSES
- A MATHEMATICAL MODEL SIMULATING THE EFFECT OF VACCINE INDUCED RESPONSES ON HIV-1 INFECTION
- Mathematical Models of the Activated Immune System during HIV Infection
- LA NICHE ÉCOLOGIQUE: CONCEPTS, MODÈLES, APPLICATIONS
- Computational structure-based methods to anticipate HIV drug resistance evolution and accelerate inhibitor discovery - eScholarship
- Measurement of insertional mutagenesis by retroviral and lentiviral vectors.
- Charakterisierung zellulärer Immunantworten von mit SIV immunisierten und infizierten Makaken
- Etude pré-clinique d'une stratégie de thérapie génique de l'infection par le VIH combinant l'expression de deux inhibiteurs d'entrée
- Models of Viral Population Dynamics.
- Viral persistence, latent reservoir, and blips: a review on HIV-1 dynamics and modeling during HAART and related treatment implications
- A mathematical growth model of the viral population in early HIV-1 infections
- A control theoretic approach to the treatment of AIDS
- Globally stable nonlinear control of HIV-1 systems
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