Embryonic stem cell lines from human blastocysts: somatic differentiation in vitro
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Summary
The derivation of pluripotent embryonic stem (ES) cells from human blastocysts is described, providing a model to study early human embryology, an investigational tool for discovery of novel growth factors and medicines, and a potential source of cells for use in transplantation therapy.
- Type
- article
- Published
- 2000-04-01
- Cited by
- 2,791
- References
- 34
- OpenAlex
- https://openalex.org/W2138442302
- Semantic Scholar
- https://api.semanticscholar.org/CorpusID:3360421
Keywords
Embryonic stem cell, Biology, KOSR, Somatic cell, Induced pluripotent stem cell
References
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- Isolation of a pluripotent cell line from early mouse embryos cultured in medium conditioned by teratocarcinoma stem cells.
- Comparative analysis of cell surface antigens expressed by cell lines derived from human germ cell tumours
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Cited by
- Recent advances in stem cell neurobiology.
- Highly efficient directed differentiation of human induced pluripotent stem cells into cardiomyocytes.
- Challenges and prospects for stem cell-based therapy in diabetes mellitus.
- Stem Cells Research: Impact on Molecular Biology of Cancer and Prospects for Therapy of Neoplastic Diseases
- Cardiomyocyte differentiation of mouse and human embryonic stem cells *
- Marker succession during the development of keratinocytes from cultured human embryonic stem cells
- Early human development: new data raise important embryological and ethical questions relevant for stem cell research
- Comparative genomic hybridization and karyotyping of human embryonic stem cells reveals the occurrence of an isodicentric X chromosome after long-term cultivation.
- Gene Expression Profiling of Embryonic Stem Cells Leads to Greater Understanding of Pluripotency and Early Developmental Events1
- Transcriptome Profiling of Human and Murine ESCs Identifies Divergent Paths Required to Maintain the Stem Cell State
- Establishment and characterization of new human embryonic stem cell lines.
- Human embryonic stem cells: Possibilities for human cell transplantation
- Characterization of a New NIH‐Registered Variant Human Embryonic Stem Cell Line, BG01V: A Tool for Human Embryonic Stem Cell Research
- Retroviral transduction of hematopoietic progenitors derived from human embryonic stem cells.
- POU5F1 Isoforms Show Different Expression Patterns in Human Embryonic Stem Cells and Preimplantation Embryos
- Heart repair and stem cells
- Human blastocyst culture and derivation of embryonic stem cell lines
- The teratoma assay: an in vivo assessment of pluripotency.
- Isolation and Characterization of a Population of Immature Dental Pulp Stem Cells Expressing OCT-4 and Other Embryonic Stem Cell Markers
- A Novel Method for Generating Xeno-Free Human Feeder Cells for Human Embryonic Stem Cell Culture
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