Cloned human teratoma cells differentiate into neuron-like cells and other cell types in retinoic acid.
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Summary
The progressively growing cells of these Tera-2 clones are capable of forming at least two types of cell: the flat cells in monolayer cultures and the neuron-like cells.
- Type
- article
- Published
- 1984-12-01
- Cited by
- 163
- References
- 94
- OpenAlex
- https://openalex.org/W1829303863
- Semantic Scholar
- https://api.semanticscholar.org/CorpusID:3238927
Keywords
Biology, Monoclonal antibody, Ganglioside, Retinoic acid, Molecular biology
References
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- Stage‐specific embryonic antigens (SSEA‐3 and ‐4) are epitopes of a unique globo‐series ganglioside isolated from human teratocarcinoma cells.
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- Use of a monoclonal antibody (W6/32) in structural studies of HLA-A,B,C, antigens.
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- Pluripotent embryonal carcinoma clones derived from the human teratocarcinoma cell line Tera-2. Differentiation in vivo and in vitro.
- Human thy-1: unusual localization and possible functional significance in lymphoid tissues.
- High affinity binding of tetanus toxin to mammalian brain membranes.
- New globoseries glycosphingolipids in human teratocarcinoma reactive with the monoclonal antibody directed to a developmentally regulated antigen, stage-specific embryonic antigen 3.
- A series of human erythrocyte glycosphingolipids reacting to the monoclonal antibody directed to a developmentally regulated antigen SSEA-1.
- Human fibronectin: molecular cloning evidence for two mRNA species differing by an internal segment coding for a structural domain.
- Two types of astrocytes in cultures of developing rat white matter: differences in morphology, surface gangliosides, and growth characteristics
- Cell surface molecules of human teratoma cell lines.
- Monoclonal antibody to a plasma membrane antigen of neurons.
- Two types of ribosome in mouse-hamster hybrid cells.
- Human embryonal carcinoma cells in culture do not synthesize fibronectin until they differentiate
- High molecular weight extracellular proteins synthesized by endoderm cells derived from mouse teratocarcinoma cells and normal extraembryonic membranes.
- A monoclonal antibody marker of human primitive endoderm
- A Monoclonal Antibody Detecting an Antigen Shared by Neural and Granulocytic Cells
- A comparative study of eight cell lines derived from human testicular teratocarcinoma
Cited by
- Different patterns of glycolipid antigens are expressed following differentiation of TERA-2 human embryonal carcinoma cells induced by retinoic acid, hexamethylene bisacetamide (HMBA) or bromodeoxyuridine (BUdR).
- The surface antigen phenotype of human embryonal carcinoma cells: modulation upon differentiation and viral infection.
- An orthotopic xenograft model of human nonseminomatous germ cell tumour
- Neuronal differentiation of retinoblastoma cells induced by medium conditioned by human RPE cells.
- Human embryonal carcinoma and yolk sac carcinoma in vitro: cell lineage relationships and possible paracrine growth regulatory interactions.
- Effects of fibroblast growth factors 19 and 20 on cell multiplication and locomotion in a human embryonal carcinoma cell line (Tera-2) in vitro.
- In vitro survival of human neoplastic germ cells.
- Growth factors and receptors during differentiation: a comparison of human and murine embryonal carcinoma cell lines.
- The influence of the extracellular matrix on cell behaviour
- Growth factors and the control of human teratoma cell proliferation.
- Stem cells in neuro-oncology--development, regeneration and treatment.
- Making Room for Stem Cells: Dissociation and Establishing New Research Objects
- Human Cancer in Primary Culture, A Handbook
- Cell Culture Methods for In Vitro Toxicology
- PDGFRA transcriptional regulation in human physiology and disease
- Differential expression of the HLA class I multigene family by human embryonal carcinoma and choriocarcinoma cell lines.
- RARβ regulates neuronal cell death and differentiation in the avian ciliary ganglion
- Developmentally regulated expression of two novel platelet-derived growth factor alpha-receptor transcripts in human teratocarcinoma cells.
- In vivo binding of retinol to chromatin. The binding is mediated by a lipoprotein.
- Mechanisms controlling TGF-Ø superfamily-induced cellular responses
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