Epigenomics and breast cancer
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- Type
- review
- Published
- 2008-12-01
- Cited by
- 179
- References
- 226
- Access
- Open access
- OpenAlex
- https://openalex.org/W2135449253
- Semantic Scholar
- https://api.semanticscholar.org/CorpusID:1633006
Keywords
Epigenetics, Epigenomics, Carcinogenesis, Biology, Histone
References
- Synergy of demethylation and histone deacetylase inhibition in the re-expression of genes silenced in cancer
- Acetylation of the C terminus of Ku70 by CBP and PCAF controls Bax-mediated apoptosis.
- Use of restriction enzymes to study eukaryotic DNA methylation: I. The methylation pattern in ribosomal DNA from Xenopus laevis.
- Methylated DNA and MeCP2 recruit histone deacetylase to repress transcription
- DNMT1 binds HDAC2 and a new co-repressor, DMAP1, to form a complex at replication foci
- Deacetylation of p53 modulates its effect on cell growth and apoptosis
- The fundamental role of epigenetic events in cancer
- DNMT1 forms a complex with Rb, E2F1 and HDAC1 and represses transcription from E2F-responsive promoters
- The Bmi-1 oncogene induces telomerase activity and immortalizes human mammary epithelial cells.
- DNMT3b overexpression contributes to a hypermethylator phenotype in human breast cancer cell lines
- Mi-2 complex couples DNA methylation to chromatin remodelling and histone deacetylation
- DNA hypomethylation leads to elevated mutation rates
- Hypermethylation of the cpG island of Ras association domain family 1A (RASSF1A), a putative tumor suppressor gene from the 3p21.3 locus, occurs in a large percentage of human breast cancers.
- Methylation of histone H3 lysine 9 creates a binding site for HP1 proteins
- Elevation of breast carcinoma Nm23-H1 metastasis suppressor gene expression and reduced motility by DNA methylation inhibition.
- Both Rb/p16INK4a inactivation and telomerase activity are required to immortalize human epithelial cells
- A gene hypermethylation profile of human cancer.
- DNA methylation in serum of breast cancer patients: an independent prognostic marker.
- Mapping of ER gene CpG island methylation-specific polymerase chain reaction.
- CDH1 promoter hypermethylation and E-cadherin protein expression in infiltrating breast cancer
Cited by
- DNA methylation in breast cancers: Differences based on estrogen receptor status and recurrence
- Association between BRCA1 polymorphisms rs799917 and rs1799966 and breast cancer risk: a meta-analysis
- Epigenetics and epidemiology: models of study and examples.
- DNA methylation profiling of fish tumours
- RNA-SEQUENCING APPLICATIONS: GENE EXPRESSION QUANTIFICATION AND METHYLATOR PHENOTYPE IDENTIFICATION
- Alcohol and breast cancer: reconciling epidemiological and molecular data.
- Biological activity of well defined hydantoin derivatives on efflux pump systems of bacteria and cancer cells
- DNA methylation and histone modifications in breast cancer.
- The role of epigenetics in the rat mammary gland
- Modulation of protein expression levels and DNA methylation status of breast cancer metastasis genes by anthracycline‐based chemotherapy and the demethylating agent decitabine
- Epigenetic Regulation of microRNA Expression: Targeting the Triple-Negative Breast Cancer Phenotype
- Methylation Status of Tumor-Related Genes in Mcf7, Mda-Mb-468 and Bt-474 Breast Cancer Cell Lines with Different Estrogen Receptor Status
- Alternative methods for regulatory toxicology – a state-of-the-art review
- Genistein inhibits DNA methylation and increases expression of tumor suppressor genes in human breast cancer cells
- Nuclear remodeling as a mechanism for genomic instability in cancer.
- The increasing roles of epigenetics in breast cancer: Implications for pathogenicity, biomarkers, prevention and treatment
- Biologic characteristics of premalignant breast disease
- Diagnostic and prognostic epigenetic biomarkers in cancer.
- Potentiation of growth inhibition and epigenetic modulation by combination of green tea polyphenol and 5-aza-2′-deoxycytidine in human breast cancer cells
- Methylated DNA and Total DNA in Serum Detected by One-Step Methylation-Specific PCR Is Predictive of Poor Prognosis for Breast Cancer Patients
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