Nuclear remodeling as a mechanism for genomic instability in cancer.
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Summary
This chapter focuses on the three-dimensional organization of the nucleus in normal, early genomically unstable, and tumor cells, and current models of nuclear remodeling are described.
- Type
- review
- Published
- 2011-01-01
- Cited by
- 31
- References
- 297
- OpenAlex
- https://openalex.org/W1605463433
- Semantic Scholar
- https://api.semanticscholar.org/CorpusID:7971267
Keywords
Genome instability, Mechanism (biology), Medicine, Instability, Cancer
References
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Cited by
- Three-dimensional Nuclear Telomere Organization in Multiple Myeloma.
- Identification of Neuroblastoma Subgroups Based on Three-Dimensional Telomere Organization
- Quantitative Microscopy to Measure the Nuclear Architecture
- A new der(1;7)(q10;p10) leading to a singular 1p loss in a case of glioblastoma with oligodendroglioma component
- 3D nuclear organization and genomic instability in cancer
- Three-dimensional telomere architecture of esophageal squamous cell carcinoma: comparison of tumor and normal epithelial cells.
- Shattered and stitched chromosomes—chromothripsis and chromoanasynthesis—manifestations of a new chromosome crisis?
- AAGAG repeat RNA is an essential component of nuclear matrix in Drosophila
- Cultivation and Differentiation Change Nuclear Localization of Chromosome Centromeres in Human Mesenchymal Stem Cells
- Chromosomal instability (CIN): what it is and why it is crucial to cancer evolution
- Spatial Localization of Genes Determined by Intranuclear DNA Fragmentation with the Fusion Proteins Lamin KRED and Histone KRED und Visible Light
- c-MYC-induced genomic instability.
- Genomic Instability: The Driving Force behind Refractory/Relapsing Hodgkin’s Lymphoma
- Regional Cell Proliferation in Microdissected Human Prostate Specimens after Heavy Water Labeling In Vivo: Correlation with Prostate Epithelial Cells Isolated from Seminal Fluid
- MYCN overexpression is associated with unbalanced copy number gain, altered nuclear location, and overexpression of chromosome arm 17q genes in neuroblastoma tumors and cell lines
- Profiling Three-Dimensional Nuclear Telomeric Architecture of Myelodysplastic Syndromes and Acute Myeloid Leukemia Defines Patient Subgroups
- XPO1 Inhibition Preferentially Disrupts the 3D Nuclear Organization of Telomeres in Tumor Cells
- The Involvement of 5-Hydroxymethylcytosine in Two DNA Metabolism Pathways: Transcription and double stranded DNA Breaks
- Genetic Heterogeneity of HER2 Amplification and Telomere Shortening in Papillary Thyroid Carcinoma
- Super‐resolution structure of DNA significantly differs in buccal cells of controls and Alzheimer's patients
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