Vanilloid (Capsaicin) receptors and mechanisms.
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Summary
This paper focuses on hot pepper, which is eaten on a daily basis by an estimated one-quarter of the world’s population and has potential to be a biological target for regenerative medicine.
- Type
- review
- Published
- 1999-06-01
- Cited by
- 1,932
- References
- 594
- OpenAlex
- https://openalex.org/W2130600650
- Semantic Scholar
- https://api.semanticscholar.org/CorpusID:35118408
Keywords
Capsaicin, Natural product, Quarter (Canadian coin), Population, Receptor
References
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- Prostaglandins and leukotrienes as inflammatory mediators.
- Hyperalgesia to heat after intradermal injection of capsaicin.
- ADVERSE CONSEQUENCES OF CAPSAICIN EXPOSURE IN HEALTH CARE WORKERS
- A P2X purinoceptor expressed by a subset of sensory neurons
- Capsaicin-induced neurotoxicity in cultured dorsal root ganglion neurons: involvement of calcium-activated proteases.
- Involvement of the sympathetic postganglionic neuron in capsaicin-induced secondary hyperalgesia in the rat.
- Capsaicin-induced activation of fine afferent fibres from rat skin in vitro.
- Capsaicin stimulates the migration of human polymorphonuclear cells (PMN) in vitro.
- Euphorbium: modern research on its active principle, resiniferatoxin, revives an ancient medicine.
- The overactive bladder: pharmacologic basis of drug treatment.
- Analysis of 50 patients with atypical odontalgia. A preliminary report on pharmacological procedures for diagnosis and treatment.
- Intravesical capsaicin in neurologic impaired patients with detrusor hyperreflexia.
- Treatment of notalgia paresthetica with capsaicin.
- Tumorigenicity and mutagenicity studies with capsaicin of hot peppers.
- Effects of orally administered capsaicin, the principal component of capsicum fruits, on the in vitro metabolism of the tobacco-specific nitrosamine NNK in hamster lung and liver microsomes.
Cited by
- Resiniferatoxin‐type phorboid vanilloids display capsaicin‐like selectivity at native vanilloid receptors on rat DRG neurons and at the cloned vanilloid receptor VR1
- Differential actions of anandamide, potassium ions and endothelium-derived hyperpolarizing factor in guinea-pig basilar artery
- Complex regulation of TRPV1 and related thermo-TRPs: implications for therapeutic intervention.
- Opioid, cannabinoid and vanilloid receptor localization on porcine cultured myenteric neurons.
- Mechanisms and physiological significance of the cholinergic control of pancreatic beta-cell function.
- Effects of vanilloid receptor agonists and antagonists on gastric antral ulcers in rats.
- Pharmacology of vanilloids at recombinant and endogenous rat vanilloid receptors.
- Pan-neurotrophin receptor p75 contributes to neuronal hyperreactivity and airway inflammation in a murine model of experimental asthma.
- Differential effects of intraplantar capsazepine and ruthenium red on capsaicin-induced desensitization in mice.
- Effect of preemptive treatment of capsaicin or resiniferatoxin on the development of pre-micturition contractions after partial urethral obstruction in the rat.
- Molecular mechanisms of trigeminal nociception and sensation of pungency.
- Contribution of natural products to the discovery of the transient receptor potential (TRP) channels family and their functions.
- Molecular mechanisms of neuropathic pain-phenotypic switch and initiation mechanisms.
- In vitro photo-release of a TRPV1 agonist.
- Pain behaviors produced by capsaicin: influence of inflammatory mediators and nerve injury.
- Structure-activity studies of a novel series of 5,6-fused heteroaromatic ureas as TRPV1 antagonists.
- Activation of Transient Receptor Potential Vanilloid Type-1 Channel Prevents Adipogenesis and Obesity
- TRP channels and pain.
- Distribution and origin of TRPV1 receptor-containing nerve fibers in the dura mater of rat.
- The Analgesic Drug, Tramadol, Acts as an Agonist of the Transient Receptor Potential Vanilloid-1
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