Genes required for mycobacterial growth defined by high density mutagenesis

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Summary

The use of transposon site hybridization (TraSH) is described to comprehensively identify the genes required by the causative agent, Mycobacterium tuberculosis, for optimal growth, suggesting that the minimal gene set required for survival varies greatly between organisms with different evolutionary histories.

Type
article
Published
2003-04-01
Cited by
2,582
References
26
Access
Open access

Keywords

Biology, Gene, Mycobacterium tuberculosis, Genome, Genetics

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