Ultrafast and memory-efficient alignment of short DNA sequences to the human genome

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Summary

Bowtie extends previous Burrows-Wheeler techniques with a novel quality-aware backtracking algorithm that permits mismatches and can be used simultaneously to achieve even greater alignment speeds.

Type
article
Published
2009-03-04
Cited by
22,290
References
32
Access
Open access

Keywords

Biology, Human genetics, Human genome, Genome, Computational biology

References

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