Role of nrf2 in oxidative stress and toxicity.

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Summary

The nuclear factor erythroid 2-related factor 2 (Nrf2) is an emerging regulator of cellular resistance to oxidants that controls the basal and induced expression of an array of antioxidant response element-dependent genes to regulate the physiological and pathophysiological outcomes of oxidant exposure.

Type
review
Published
2013-01-07
Cited by
4,527
References
171
Access
Open access

Keywords

Oxidative stress, Reactive oxygen species, Antioxidant, Cell biology, Signal transduction

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