Inherited variant on chromosome 11q23 increases susceptibility to IDH-mutated but not IDH-normal gliomas regardless of grade or histology.
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Summary
A variant at the 11q23 locus increases risk forIDH-mutated but not IDH-wild-type gliomas, regardless of grade or histology.
- Type
- article
- Published
- 2013-05-01
- Cited by
- 37
- References
- 34
- Access
- Open access
- OpenAlex
- https://openalex.org/W2115701263
- Semantic Scholar
- https://api.semanticscholar.org/CorpusID:17278198
Keywords
Glioma, Biology, Histology, Genetics, Pathology
References
- WHO classification of tumours of the central nervous system
- Combinations of newly confirmed Glioma-Associated loci link regions on chromosomes 1 and 9 to increased disease risk
- Metabolism unhinged: IDH mutations in cancer
- All the 1p19q codeleted gliomas are mutated on IDH1 or IDH2
- Molecular subclassification of diffuse gliomas: Seeing order in the chaos
- IDH1 mutation is sufficient to establish the glioma hypermethylator phenotype
- Combined molecular analysis of BRAF and IDH1 distinguishes pilocytic astrocytoma from diffuse astrocytoma
- A comprehensive study of the association between the EGFR and ERBB2 genes and glioma risk
- Cancer susceptibility variants and the risk of adult glioma in a US case–control study
- Genetic risk profiles identify different molecular etiologies for glioma
- Genome-wide association study identifies five susceptibility loci for glioma
- A germline JAK2 SNP is associated with predisposition to the development of JAK2V617F-positive myeloproliferative neoplasms
- An Integrated Genomic Analysis of Human Glioblastoma Multiforme
- Isocitrate dehydrogenase 1 and 2 mutations in cholangiocarcinoma.
- A common variant at the TERT-CLPTM1L locus is associated with estrogen receptor–negative breast cancer
- A germline variant in the TP53 polyadenylation signal confers cancer susceptibility
- Isocitrate dehydrogenase mutations in diffuse gliomas: clinical and aetiological implications
- Evidence for sequenced molecular evolution of IDH1 mutant glioblastoma from a distinct cell of origin.
- IDH1 or IDH2 mutations predict longer survival and response to temozolomide in low-grade gliomas
- Distinct germline polymorphisms underlie glioma morphologic heterogeneity
Cited by
- Epidemiology of gliomas.
- Genotype-phenotype studies in brain tumors
- Glioma Groups Based on 1p/19q, IDH, and TERT Promoter Mutations in Tumors
- An Updated and Comprehensive Meta-Analysis of Association Between Seven Hot Loci Polymorphisms from Eight GWAS and Glioma Risk
- The PHLDB1 rs498872 (11q23.3) polymorphism and glioma risk: A meta‐analysis
- Serum macrophage-derived chemokine/CCL22 levels are associated with glioma risk, CD4 T cell lymphopenia and survival time
- Telomere maintenance and the etiology of adult glioma.
- Survival and low grade glioma: the emergence of genetic information
- Genetic variants in telomerase-related genes are associated with an older age at diagnosis in glioma patients: evidence for distinct pathways of gliomagenesis.
- From GWAS risk foci to glioma molecular subclass.
- CDKN2A Loss Is Associated with Shortened Overall Survival in Lower Grade (World Health Organization II-III) Astrocytomas
- Molecular Markers in Low Grade Glioma – Toward Tumor Reclassification
- Genetics in glioma- lessons learned from genome wide association studies
- The epidemiology of glioma in adults: a "state of the science" review.
- Assessment of Glioma Risk Associated with an Inherited Variant at Chromosome 11q23
- What do we know about IDH1/2 mutations so far, and how do we use it?
- Understanding inherited genetic risk of adult glioma - a review.
- Chapter 1 - Epidemiology
- Rare ADAR and RNASEH2B variants and a type I interferon signature in glioma and prostate carcinoma risk and tumorigenesis
- Genome-Wide Association Studies in Glioma
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